Department of Anesthesiology, University of Szeged, 6720, Hungary.
J Crit Care. 2010 Sep;25(3):541.e9-15. doi: 10.1016/j.jcrc.2009.12.002. Epub 2010 Feb 10.
This study provides practical experiences with a new, simple, balloon-free gastric tonometric probe (probe) and reports the results of simultaneous in vitro and in vivo measurements with a conventional, ballooned gastric air tonometer (catheter) and the new device.
Ten healthy volunteers and 50 anesthetized surgical patients with different American Society of Anesthesiologists (ASA) scores, scheduled for neurologic, orthopedic, trauma, and cardiac operations, were enrolled in the study. The values of 60 in vitro and, in 12 surgical patients, 101 in vivo paired Pco(2) measurements--performed simultaneously with the new tonometric probe and the catheter that was connected to a Tonocap monitor--were compared. The tolerability of the measurement with the new probe was examined, and the results of gastric tonometry and, in surgical cases, the gastric tonometric, end-expiratory, and arterial Pco(2) values were registered. The results were evaluated by analysis of variance test. The data of the in vivo paired measurements were evaluated by Bland-Altman analysis.
The use of the probe proved to be well tolerated and easily applicable in the studied cases. The results of 20 measurements obtained in healthy volunteers and those of 520 measurements in the surgical cases correspond to the data obtained with the classical methods published in the medical literature. During in vitro paired measurements, there was a good agreement between the data obtained with the 2 methods; however, in the in vivo studies, the results of measurements performed with the probe were mostly higher.
The differences between the results obtained with the 2 methods might have been caused by the quicker equilibration property of the probe and by the fundamental differences between the 2 methods. The new probe seems to be applicable for routine human measurements.
本研究提供了一种新的、简单的无球囊胃测压探头（探头）的实际应用经验，并报告了与传统的带气囊胃测压管（导管）和新装置同时进行的体外和体内测量结果。
本研究纳入了 10 名健康志愿者和 50 名接受不同美国麻醉医师协会（ASA）评分的麻醉手术患者，这些患者计划进行神经、骨科、创伤和心脏手术。进行了 60 次体外和 12 例手术患者的 101 次体内配对 Pco（2）测量，这些测量是使用新的测压探头和与 Tonocap 监测器相连的导管同时进行的。研究检查了使用新探头进行测量的耐受性，并记录了胃测压的结果，以及在手术病例中，胃测压、呼气末和动脉 Pco（2）值。结果通过方差分析进行评估。体内配对测量的数据通过 Bland-Altman 分析进行评估。
在研究病例中，探头的使用被证明是耐受良好且易于应用的。在健康志愿者中进行的 20 次测量和手术患者中的 520 次测量的结果与发表在医学文献中的经典方法的数据相对应。在体外配对测量中，两种方法获得的数据之间存在良好的一致性；然而，在体内研究中，探头测量的结果大多更高。
两种方法获得的结果之间的差异可能是由于探头更快的平衡特性和两种方法之间的基本差异造成的。新探头似乎适用于常规的人体测量。
