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一种新开发的用于评估组织灌注的舌下眼压测量方法及其体外和健康人体体内验证以及慢性阻塞性肺疾病(COPD)患者的测量结果

A Newly Developed Sublingual Tonometric Method for the Evaluation of Tissue Perfusion and Its Validation In Vitro and in Healthy Persons In Vivo and the Results of the Measurements in COPD Patients.

作者信息

Rózsavölgyi Zoltán, Boda Domokos, Hajnal Andrea, Boda Krisztina, Somfay Attila

机构信息

Department of Pulmonology, University of Szeged, 36 Alkotmány Street, Deszk 6772, Hungary.

Department of Pediatrics, University of Szeged, Korányi Fasor 14, Szeged 6720, Hungary.

出版信息

Crit Care Res Pract. 2014;2014:534130. doi: 10.1155/2014/534130. Epub 2014 Dec 16.

DOI:10.1155/2014/534130
PMID:25580290
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4280804/
Abstract

Introduction. Since its first publication in the medical literature, an extremely large number of references have demonstrated that the tonometric measurement of tissue perfusion is a reliable indicator of the actual condition of critically ill patients. Later a new method was developed by the introduction of sublingual tonometry for the determination of tissue perfusion. In comparison with gastric tonometry, the new method was simpler and could even be used in awake patients. Unfortunately, at present, because of severe failures of manufacturing, the device is withdrawn from commerce. Materials and Methods. In this study, we present a new method using a newly developed tool for the PslCO2 measurement in sublingual tonometry as well as the data for its validation in vitro and in vivo and the results of 25 volunteers and 54 COPD patients belonging to different GOLD groups at their hospitalization due to the acute exacerbation of the disease but already in a stable condition at the time of the examination. Results and Conclusion. The results of the performed examinations showed that the method is suitable for monitoring the actual condition of the patients by mucosal perfusion tonometry in the sublingual region.

摘要

引言。自其首次在医学文献中发表以来,大量参考文献表明,组织灌注的眼压测量法是危重症患者实际状况的可靠指标。后来,通过引入舌下眼压测量法来测定组织灌注,开发出了一种新方法。与胃内眼压测量法相比,新方法更简单,甚至可用于清醒患者。不幸的是,目前由于制造上的严重故障,该设备已退出商业市场。材料与方法。在本研究中,我们提出一种新方法,该方法使用一种新开发的工具进行舌下眼压测量中的PslCO2测量,以及其体外和体内验证数据,还有25名志愿者和54名属于不同GOLD组的慢性阻塞性肺疾病(COPD)患者在因疾病急性加重住院但检查时已处于稳定状态的数据。结果与结论。所进行检查的结果表明,该方法适用于通过舌下区域的黏膜灌注眼压测量法监测患者的实际状况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6562/4280804/fc0a25cb53da/CCRP2014-534130.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6562/4280804/9325f67a9937/CCRP2014-534130.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6562/4280804/fc0a25cb53da/CCRP2014-534130.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6562/4280804/9325f67a9937/CCRP2014-534130.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6562/4280804/fc0a25cb53da/CCRP2014-534130.002.jpg

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A Newly Developed Sublingual Tonometric Method for the Evaluation of Tissue Perfusion and Its Validation In Vitro and in Healthy Persons In Vivo and the Results of the Measurements in COPD Patients.一种新开发的用于评估组织灌注的舌下眼压测量方法及其体外和健康人体体内验证以及慢性阻塞性肺疾病(COPD)患者的测量结果
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Recent Advances of Mucosal Capnometry and the Perspectives of Gastrointestinal Monitoring in the Critically Ill. A Pilot Study.黏膜二氧化碳测定法的最新进展及危重症患者胃肠道监测的前景。一项初步研究。
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Practical experiences and in vitro and in vivo validation studies with a new gastric tonometric probe in human adult patients.新型成人患者胃测压探头的临床应用经验及在体、离体验证研究。
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