INSERM, U912 Economic & Social Sciences, Health Systems & Societies, Paoli-Calmettes Institute, Marseille, France.
Psychooncology. 2011 Jan;20(1):12-8. doi: 10.1002/pon.1714.
To determine the procreational intention rates among cancer survivors whose fertility was unimpaired and to identify the factors associated with their procreational intentions.
Six thousand nine hundred and fifty-seven adult cancer patients treated between September and October 2002 were randomly selected from the French National Health Insurance Fund's Chronic Disease File. Of the 6957, 4270 responded to a cross-sectional questionnaire 2 years after diagnosis, of whom 959 reported being fertile and responded to a question about their procreational intentions.
Among the 257 male and female survivors aged 20-44, 86 (33.5%) had procreational intentions. After adjusting for age, gender, and already having children, only a high educational level (adjusted odds ratio: 3.1, 95% confidence interval 1.3-7.8) and stable or increasing financial resources (2.4, 1.0-5.7) were independently associated with the respondents' procreational intentions. Neither cancer stage at diagnosis nor the present stage significantly affected their plans in this respect.
Two years after cancer diagnosis, the reasons why some survivors who are still fertile have no parenthood projects were similar to those earlier given by members of the general population.
确定生育能力未受影响的癌症幸存者的生育意愿率，并确定与他们生育意愿相关的因素。
从法国国家健康保险基金慢性病档案中随机抽取 2002 年 9 月至 10 月间治疗的 6957 名成年癌症患者。在 6957 名患者中，有 4270 名在诊断后 2 年回复了横断面问卷调查，其中 959 名报告自己有生育能力，并回答了一个关于生育意愿的问题。
在 257 名 20-44 岁的男女幸存者中，有 86 人（33.5%）有生育意愿。在调整了年龄、性别和已有子女数后，只有高教育水平（调整后的优势比：3.1，95%置信区间 1.3-7.8）和稳定或增加的经济资源（2.4，1.0-5.7）与受访者的生育意愿独立相关。诊断时的癌症分期和目前的分期都没有显著影响他们在这方面的计划。
在癌症诊断后 2 年，一些仍然有生育能力的幸存者没有生育计划的原因与一般人群中早些时候给出的原因相似。
