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噪声性高血压的剂量反应关系。

A dose response relation for noise induced hypertension.

作者信息

Zhao Y M, Zhang S Z, Selvin S, Spear R C

机构信息

Cardiovascular Research Laboratory, Third Hospital, Beijing Medical University, People's Republic of China.

出版信息

Br J Ind Med. 1991 Mar;48(3):179-84. doi: 10.1136/oem.48.3.179.

Abstract

The effect of industrial noise on the prevalence of hypertension was studied in a group of 1101 female workers in a textile mill in Beijing in 1985. Essentially the entire group had worked in specific workshops in this mill for all their working lives and all had worked for at least five years. The noise levels within the plant were assessed and appear to have been constant since 1954 resulting in well defined noise exposures for these workers. A cross sectional design was used in which blood pressures were determined and questionnaires administered to the workers over a two month period. As well as demographic information, data were gathered on personal and family history of hypertension, current use of prescription drugs, alcohol, tobacco, and salt in the diet. Logistic regression indicated that exposure to noise is a significant determinant of prevalence of hypertension, but third in order of importance behind family history of hypertension and use of salt. Each of the predictor variables exerted an independent influence on risk of hypertension. Cumulative exposure to noise was not an important dose related variable suggesting that, for those susceptible to the effect, hypertension was manifested within the first five years of exposure.

摘要

1985年,对北京一家纺织厂的1101名女工进行了研究,以探讨工业噪声对高血压患病率的影响。基本上,整个群体一生都在该厂的特定车间工作,且所有人都至少工作了五年。对工厂内的噪声水平进行了评估,自1954年以来似乎一直保持不变,从而使这些工人有明确的噪声暴露情况。采用横断面设计,在两个月的时间里测定了工人们的血压并发放了问卷。除了人口统计学信息外,还收集了有关高血压个人和家族病史、当前处方药使用情况、酒精、烟草和饮食中盐的摄入的数据。逻辑回归表明,噪声暴露是高血压患病率的一个重要决定因素,但在重要性排序上排在高血压家族病史和盐的摄入量之后,位列第三。每个预测变量都对高血压风险产生独立影响。噪声的累积暴露不是一个重要的剂量相关变量,这表明,对于那些易受影响的人来说,高血压在暴露的头五年内就会显现出来。

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