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代谢手术与营养缺乏

Metabolic surgery and nutritional deficiencies.

作者信息

Stroh Christine, Manger Thomas, Benedix Frank

机构信息

Department of General, Visceral and Children Surgery, SRH Hospital, Gera, Germany - Christine.Stroh@.srh.de.

Department of General, Visceral and Children Surgery, SRH Hospital, Gera, Germany.

出版信息

Minerva Chir. 2017 Oct;72(5):432-441. doi: 10.23736/S0026-4733.17.07408-9. Epub 2017 May 30.

Abstract

The increasing prevalence of morbid obesity in Germany is associated with an increasing number of metabolic surgical interventions. Short-term surgical and long-term metabolic complications such as nutrient deficiencies can be considered as the main risks of metabolic surgery with its malabsorptive but also restrictive procedures. The aim of this review was to characterize the most relevant metabolic complications specific for the various bariatric procedures, which, subsequently, require a permanent surveillance and supplementation, respectively. Furthermore, we aimed to identify if there are diagnostic and therapeutic measures that can prevent those complications. Restrictive bariatric surgery such as "gastric banding" and "sleeve gastrectomy" can be associated with deficiencies related to B-vitamins whereas iron, folate, vitamin B1, B12 and D deficiencies are associated with the malabsorptive procedure such as "biliopancreatic diversion," "duodenal switch" and "Roux-en-Y gastric bypass". Due to possible metabolic and surgical complications after bariatric surgery, patients need to undergo life-long medical and dietetic surveillance. The recently published guidelines of the "American Association of Bariatric and Metabolic Surgery" are the basis for recommendations on supplementation and treatment following weight loss surgery.

摘要

德国病态肥胖症患病率的上升与代谢手术干预数量的增加相关。短期手术并发症以及诸如营养缺乏等长期代谢并发症可被视为代谢手术的主要风险,代谢手术包括吸收不良型手术以及限制型手术。本综述的目的是描述各种减肥手术特有的最相关代谢并发症,这些并发症随后分别需要长期监测和补充治疗。此外,我们旨在确定是否存在可预防这些并发症的诊断和治疗措施。诸如“胃束带术”和“袖状胃切除术”等限制型减肥手术可能与B族维生素缺乏有关,而铁、叶酸、维生素B1、B12和D缺乏与诸如“胆胰分流术”、“十二指肠转位术”和“Roux-en-Y胃旁路术”等吸收不良型手术有关。由于减肥手术后可能出现代谢和手术并发症,患者需要接受终身医疗和饮食监测。“美国减肥与代谢外科学会”最近发布的指南是减肥手术后补充治疗和治疗建议的基础。

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