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西门子免疫散射比浊法检测免疫球蛋白 G 及其亚类的儿科参考区间。

Pediatric reference intervals for immunoglobulin G and its subclasses with Siemens immunonephelometric assays.

机构信息

Department of Pathology and Laboratory Medicine, Children's Hospital of Eastern Ontario, Ottawa, Canada.

出版信息

Clin Biochem. 2010 May;43(7-8):694-6. doi: 10.1016/j.clinbiochem.2010.02.003. Epub 2010 Feb 12.

Abstract

OBJECTIVE

To determine the pediatric reference intervals for the Dade Behring IgG subclass reagents.

DESIGN AND METHODS

Blood samples of healthy children and adolescents were analyzed to determine the level of immunoglobulin G (IgG) and the IgG subclass using the reagents of Dade Behring Marburg GmbH.

RESULTS

The reference intervals categorized by age were reported from a total of 436 samples. There was an excellent correlation between the total IgG and the sum of the IgG subclasses.

CONCLUSIONS

Our data provide the missing pediatric reference intervals and enable the use of the Dade Behring nephelometric IgG subclass reagents in children and adolescents.

摘要

目的

确定达亚美宝 IgG 亚类试剂的儿科参考区间。

设计与方法

分析健康儿童和青少年的血样,使用达亚美宝 Marburg GmbH 的试剂来确定免疫球蛋白 G(IgG)和 IgG 亚类的水平。

结果

共有 436 个样本的参考区间按年龄分类报告。总 IgG 与 IgG 亚类总和之间具有极好的相关性。

结论

我们的数据提供了缺失的儿科参考区间,使达亚美宝散射免疫比浊法 IgG 亚类试剂能够用于儿童和青少年。

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