Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan.
J Epidemiol. 2010;20(2):90-6. doi: 10.2188/jea.je20090209. Epub 2010 Feb 13.
In Japan, cancer has long been recognized as a major component of the overall pattern of disease. Currently, there is a need to implement practical control measures with specific numerical targets appropriate for the Japanese population. Using data from the Japan Public Health Center-based Prospective Study, the author estimated the impact of major risk factors on overall cancer risk among a Japanese population. These risk factors included tobacco smoking, alcohol drinking, body mass index, history of diabetes, physical activity, and metabolic factors and their aggregates. The results show that tobacco smoking and heavy alcohol drinking were significantly positively associated with overall cancer risk, and that total physical activity was significantly inversely associated with the risk of cancer. Although people with a history of diabetes may be at increased risk of cancer, extreme body mass index and metabolic factors in the aggregate had little impact on overall cancer risk in the Japanese population.
在日本，癌症一直被认为是整体疾病模式的一个主要组成部分。目前，需要针对日本人口实施具有特定数字目标的实用控制措施。作者使用来自日本公共卫生中心前瞻性研究的数据，估计了主要危险因素对日本人群整体癌症风险的影响。这些危险因素包括吸烟、饮酒、体重指数、糖尿病史、身体活动以及代谢因素及其总和。结果表明，吸烟和大量饮酒与整体癌症风险显著正相关，而总身体活动与癌症风险显著负相关。尽管有糖尿病史的人可能癌症风险增加，但极端的体重指数和代谢因素总和对日本人群的整体癌症风险影响不大。
