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一期后路内固定手术治疗伴神经功能缺损的骨质疏松性椎体塌陷。

One-stage posterior instrumentation surgery for the treatment of osteoporotic vertebral collapse with neurological deficits.

机构信息

Department of Advanced Medicine for Spine and Spinal Cord Disorders, Graduate School of Medicine, Hokkaido University, North-15, West-7, Kita-ku, Sapporo, Hokkaido, 060-8638, Japan.

出版信息

Eur Spine J. 2010 Jun;19(6):907-15. doi: 10.1007/s00586-010-1318-9. Epub 2010 Feb 16.

Abstract

The number of reports describing osteoporotic vertebral fracture has increased as the number of elderly people has grown. Anterior decompression and fusion alone for the treatment of vertebral collapse is not easy for patients with comorbid medical problems and severe bone fragility. The purpose of the present study was to evaluate the efficacy of one-stage posterior instrumentation surgery for the treatment of osteoporotic vertebral collapse with neurological deficits. A consecutive series of 21 patients who sustained osteoporotic vertebral collapse with neurological deficits were managed with posterior decompression and short-segmental pedicle screw instrumentation augmented with ultra-high molecular weight polyethylene (UHMWP) cables with or without vertebroplasty using calcium phosphate cement. The mean follow-up was 42 months. All patients showed neurologic recovery. Segmental kyphotic angle at the instrumented level was significantly improved from an average preoperative kyphosis of 22.8-14.7 at a final follow-up. Spinal canal occupation was significantly reduced from an average before surgery of 40.4-19.1% at the final follow-up. Two patients experienced loosening of pedicle screws and three patients developed subsequent vertebral compression fractures within adjacent segments. However, these patients were effectively treated in a conservative fashion without any additional surgery. Our results indicated that one-stage posterior instrumentation surgery augmented with UHMWP cables could provide significant neurological improvement in the treatment of osteoporotic vertebral collapse.

摘要

随着老年人口的增加,描述骨质疏松性椎体骨折的报告数量有所增加。对于患有合并症和严重骨脆弱的患者,单纯进行前路减压和融合治疗椎体塌陷并不容易。本研究的目的是评估一期后路器械手术治疗伴有神经功能缺损的骨质疏松性椎体塌陷的疗效。对 21 例伴有神经功能缺损的骨质疏松性椎体塌陷患者进行了连续系列治疗,采用后路减压和短节段椎弓根螺钉器械固定,辅以超高分子量聚乙烯(UHMWP)电缆,或使用磷酸钙骨水泥进行骨水泥强化。平均随访 42 个月。所有患者均出现神经恢复。在终末随访时,器械水平的节段后凸角从术前平均后凸 22.8°-14.7°显著改善。椎管占位率从术前平均 40.4%-19.1%显著降低。2 例患者发生椎弓根螺钉松动,3 例患者相邻节段发生后续椎体压缩骨折。然而,这些患者通过保守治疗得到了有效治疗,无需进行任何额外的手术。我们的结果表明,一期后路器械手术辅以 UHMWP 电缆可在治疗骨质疏松性椎体塌陷方面提供显著的神经改善。

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