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用于植入式脑微机电系统可移动微电极的柔性芯片级封装与互连。

Flexible Chip Scale Package and Interconnect for Implantable MEMS Movable Microelectrodes for the Brain.

作者信息

Jackson Nathan, Muthuswamy Jit

机构信息

Harrington Department of Bioengineering, Arizona State University, Tempe, AZ 85287.

出版信息

J Microelectromech Syst. 2009 Apr 1;18(2):396-404. doi: 10.1109/JMEMS.2009.2013391.

Abstract

We report here a novel approach called MEMS microflex interconnect (MMFI) technology for packaging a new generation of Bio-MEMS devices that involve movable microelectrodes implanted in brain tissue. MMFI addresses the need for (i) operating space for movable parts and (ii) flexible interconnects for mechanical isolation. We fabricated a thin polyimide substrate with embedded bond-pads, vias, and conducting traces for the interconnect with a backside dry etch, so that the flexible substrate can act as a thin-film cap for the MEMS package. A double gold stud bump rivet bonding mechanism was used to form electrical connections to the chip and also to provide a spacing of approximately 15-20 µm for the movable parts. The MMFI approach achieved a chip scale package (CSP) that is lightweight, biocompatible, having flexible interconnects, without an underfill. Reliability tests demonstrated minimal increases of 0.35 mΩ, 0.23 mΩ and 0.15 mΩ in mean contact resistances under high humidity, thermal cycling, and thermal shock conditions respectively. High temperature tests resulted in an increase in resistance of > 90 mΩ when aluminum bond pads were used, but an increase of ~ 4.2 mΩ with gold bond pads. The mean-time-to-failure (MTTF) was estimated to be at least one year under physiological conditions. We conclude that MMFI technology is a feasible and reliable approach for packaging and interconnecting Bio-MEMS devices.

摘要

我们在此报告一种名为MEMS微挠性互连(MMFI)技术的新方法,用于封装新一代生物微机电系统(Bio - MEMS)设备,这些设备包含植入脑组织中的可移动微电极。MMFI满足了以下需求:(i)为可移动部件提供操作空间;(ii)提供用于机械隔离的柔性互连。我们制造了一种带有嵌入式焊盘、过孔和导电迹线的薄聚酰亚胺基板,通过背面干法蚀刻实现互连,从而使柔性基板可作为MEMS封装的薄膜盖。采用双金柱凸点铆接机制来形成与芯片的电气连接,同时为可移动部件提供约15 - 20 µm的间距。MMFI方法实现了一种芯片级封装(CSP),该封装重量轻、具有生物相容性、有柔性互连且无需底部填充。可靠性测试表明,在高湿度、热循环和热冲击条件下,平均接触电阻分别仅增加0.35 mΩ、0.23 mΩ和0.15 mΩ。高温测试中,使用铝焊盘时电阻增加> 90 mΩ,而使用金焊盘时电阻增加约4.2 mΩ。在生理条件下,平均无故障时间(MTTF)估计至少为一年。我们得出结论,MMFI技术是用于封装和互连Bio - MEMS设备的一种可行且可靠的方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f5a9/2761039/04361210425d/nihms89140f1.jpg

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