芳炔与甲亚胺叶立德的1,3-偶极环加成反应：1,2-二氢吡唑并[1,2-a]吲唑-3(9H)-酮的合成
1,3-Dipolar cycloaddition of arynes with azomethine imines: synthesis of 1,2-dihydropyrazolo[1,2-a]indazol-3(9H)-ones.
作者信息
Shi Feng, Mancuso Raffaella, Larock Richard C
机构信息
Department of Chemistry, Iowa State University, Ames, IA 50011, USA.
出版信息
Tetrahedron Lett. 2009 Jul 15;50(28):4067-4070. doi: 10.1016/j.tetlet.2009.04.102.
Abstract
A [3+2] 1,3-dipolar cycloaddition reaction of arynes with stable azomethine imines has been developed. The reaction rapidly assembles tricyclic pyrazoloindazolone derivatives in moderate yields under mild reaction conditions.
摘要
已开发出一种芳烃与稳定的甲亚胺亚胺的[3 + 2] 1,3 - 偶极环加成反应。该反应在温和的反应条件下能快速组装出三环吡唑并吲唑酮衍生物，产率适中。
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