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火绳树叶片的酚类化合物及其生物活性

Phenolic compounds and bioactivity of leaves of Mayodendron igneum Kurz.

作者信息

Hashem F A, el-Sawi S A, Sleem A A

机构信息

Pharmacognosy Department, National Research Centre, Dokki, Cairo, Egypt.

出版信息

Afr J Tradit Complement Altern Med. 2007 Feb 16;4(3):306-12.

Abstract

Four apigenin glycosides were isolated from the ethyl acetate extract of the leaves of Mayodendron igneum Fam.Bignoniaceae. They were identified as apigenin 7-O-glucoside; 6-methoxy apigenin-7-O-glucoside; 6-methoxy apigenin-7-O-rhamnoglucoside and 6-hydroxy apigenin-7-O-rhamnoglucoside. In addition an isoflavone glycoside was isolated, and identified as genistin 5,4'-methyl ether. Ethanol (80%) extract of Mayodendron igneum leaves exhibited significant anti-inflammatory and analgesic activities. LD(50) determination of the extract indicated the safety of the leaves of the plant.

摘要

从紫葳科火焰树的叶子乙酸乙酯提取物中分离出四种芹菜素糖苷。它们被鉴定为芹菜素7-O-葡萄糖苷、6-甲氧基芹菜素-7-O-葡萄糖苷、6-甲氧基芹菜素-7-O-鼠李糖葡萄糖苷和6-羟基芹菜素-7-O-鼠李糖葡萄糖苷。此外,还分离出一种异黄酮糖苷,并鉴定为染料木苷5,4'-甲醚。火焰树叶子的乙醇(80%)提取物表现出显著的抗炎和镇痛活性。提取物的半数致死量(LD50)测定表明该植物叶子的安全性。

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