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非洲天门冬根提取物的镇痛和抗炎活性。

Analgesic and anti-inflammatory activities of Asparagus africanus root extract.

作者信息

Hassan Hs, Ahmadu A A, Hassan A S

机构信息

Dept of Pharmaceutical and Medicinal Chemistry, Ahmadu Bello University, Zaria.

出版信息

Afr J Tradit Complement Altern Med. 2007 Oct 27;5(1):27-31. doi: 10.4314/ajtcam.v5i1.31252.

Abstract

The methanolic extract of the roots of Asparagus africanus Lam (Liliaceae) which contains mainly saponins and carbohydrate showed significant analgesic and anti-inflammatory activities (P<0.05) in the tail-flick/hot-plate test and egg albumen-induced rat paw oedema tests that were comparable to the test drugs (morphine 20 mg/kg and indomethacin 50 mg/kg respectively). These results indicate that the extract possesses analgesic and anti-inflammatory properties.

摘要

非洲天门冬(百合科)根的甲醇提取物主要含有皂苷和碳水化合物,在甩尾/热板试验以及蛋清诱导的大鼠足肿胀试验中显示出显著的镇痛和抗炎活性(P<0.05),与受试药物(分别为吗啡20mg/kg和吲哚美辛50mg/kg)相当。这些结果表明该提取物具有镇痛和抗炎特性。

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