将纳米多孔聚合物膜不可逆地直接键合到 PDMS 或玻璃微器件上。
Irreversible, direct bonding of nanoporous polymer membranes to PDMS or glass microdevices.
机构信息
Department of Biomedical Engineering, Rutgers University, 599 Taylor Road, Piscataway, NJ 08854, USA.
出版信息
Lab Chip. 2010 Mar 7;10(5):548-52. doi: 10.1039/b924816a. Epub 2010 Jan 7.
Abstract
A method for integrating porous polymer membranes such as polycarbonate, polyethersulfone and polyethylene terephthalate to microfluidic devices is described. The use of 3-aminopropyltriethoxysilane as a chemical crosslinking agent was extended to integrate membranes with PDMS and glass microfluidic channels. A strong, irreversible bond between the membranes and microfluidic structure was achieved. The bonding strength in the APTES treated devices was significantly greater than in devices fabricated using either a PDMS "glue" or two-part epoxy bonding method. Evaluation of a filtering microdevice and the pore structure via SEM indicates the APTES conjugation does not significantly alter the membrane transport function and pore morphology.
摘要
描述了一种将多孔聚合物膜（如聚碳酸酯、聚醚砜和聚对苯二甲酸乙二醇酯）集成到微流控器件中的方法。将 3-氨丙基三乙氧基硅烷用作化学交联剂，以将膜与 PDMS 和玻璃微流控通道集成在一起。在膜和微流控结构之间实现了牢固的、不可逆的键合。在经过 APTES 处理的器件中，键合强度明显大于使用 PDMS“胶”或双组分环氧树脂键合方法制造的器件。通过 SEM 对过滤微器件和孔结构进行评估表明，APTES 缀合不会显著改变膜传输功能和孔形态。
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