Program in Cognitive Neuroscience, Department of Psychology, City College of the City University of New York, New York, USA.
Hum Brain Mapp. 2010 Nov;31(11):1813-21. doi: 10.1002/hbm.20983.
Neuroimaging studies investigating somatosensory-based object recognition in humans have revealed activity in the lateral occipital complex, a cluster of regions primarily associated with visual object recognition. To date, determining whether this activity occurs during or subsequent to recognition per se, has been difficult to assess due to the low temporal resolution of the hemodynamic response. To more finely measure the timing of somatosensory object recognition processes we employed high density EEG using a modified version of a paradigm previously applied to neuroimaging experiments. Simple geometric shapes were presented to the right index finger of 10 participants while the ongoing EEG was measured time locked to the stimulus. In the condition of primary interest participants discriminated the shape of the stimulus. In the alternate condition they judged stimulus duration. Using traditional event-related potential analysis techniques we found significantly greater amplitudes in the evoked potentials of the shape discrimination condition between 140 and 160 ms, a timeframe in which LOC mediated perceptual processes are believed to occur during visual object recognition. Scalp voltage topography and source analysis procedures indicated the lateral occipital complex as the likely source behind this effect. This finding supports a multisensory role for the lateral occipital complex during object recognition.
神经影像学研究表明，人类的基于体感的物体识别涉及外侧枕叶复合体的活动，该区域集群主要与视觉物体识别有关。迄今为止，由于血液动力学反应的时间分辨率较低，很难评估这种活动是在识别本身期间还是之后发生。为了更精确地测量体感物体识别过程的时间，我们使用高密度 EEG 并采用先前应用于神经影像学实验的一种修正范式。10 名参与者的右手食指接受简单的几何形状呈现，而持续的 EEG 则与刺激时间锁定进行测量。在主要关注的条件下，参与者区分了刺激的形状。在交替条件下，他们判断刺激的持续时间。使用传统的事件相关电位分析技术，我们发现形状辨别条件下的诱发电位在 140 到 160 毫秒之间的振幅显著增加，这一时间范围内，外侧枕叶复合体被认为在视觉物体识别过程中发生知觉过程。头皮电压地形和源分析程序表明，外侧枕叶复合体是这种效应的可能来源。这一发现支持了外侧枕叶复合体在物体识别过程中的多感觉作用。
