Molecular Foundry, Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Berkeley, California 94720, USA.
J Am Chem Soc. 2010 Mar 17;132(10):3248-9. doi: 10.1021/ja9101198.
Here we demonstrate Au nanoparticle self-similar chain structure organized by triangle DNA origami with well-controlled orientation and <10 nm spacing. We show for the first time that a large DNA complex (origami) and multiple AuNP conjugates can be well-assembled and purified with reliable yields. The assembled structure could be used to generate high local-field enhancement. The same method can be used to precisely localize multiple components on a DNA template for potential applications in nanophotonic, nanomagnetic, and nanoelectronic devices.
在这里，我们展示了由三角形 DNA 折纸组织的具有良好控制取向和 <10nm 间距的金纳米粒子自相似链结构。我们首次表明，可以使用可靠的产率对大型 DNA 复合物（折纸）和多个 AuNP 缀合物进行良好的组装和纯化。组装结构可用于产生高局域场增强。相同的方法可用于在 DNA 模板上精确定位多个组件，为纳米光子学、纳米磁性和纳米电子设备中的潜在应用提供了可能。
