Werder Peter, Altermatt Hans Jörg, Zbären Peter, Mueller-Garamvölgyi Esther, Bornstein Michael M
Department of Oral Surgery and Stomatology, School of Dental Medicine, University of Bern, and Department of ENT, Head and and Neck Surgery, University Hospital, Inselspital, Bern, Switzerland.
Quintessence Int. 2010 Feb;41(2):93-7.
Non-Hodgkin lymphomas (NHLs) in the head and neck region are malignant lymphoid neoplasms that usually originate from B-lymphocytic cell lines. Primary extranodal manifestations of this hematolymphoid tumor in the oral cavity are rare and involve the maxillary jaw including the palatal soft tissues, the mandible, and gingival tissues in patients between 60 and 70 years of age without sex predilection. This case report of an extra-nodal NHL in the palate of a 75-year-old patient emphasizes the importance of accurate clinical, radiographic, and histologic diagnostic procedures to avoid delayed diagnosis or inappropriate treatment strategies. Chemotherapy, radiotherapy, or a combination of the two with a regular clinical and hemic follow-up is recommended.
头颈部非霍奇金淋巴瘤（NHLs）是通常起源于B淋巴细胞系的恶性淋巴肿瘤。这种血液淋巴肿瘤在口腔的原发性结外表现罕见，累及上颌骨包括腭部软组织、下颌骨以及60至70岁无性别倾向患者的牙龈组织。本病例报告了一名75岁患者腭部的结外NHL，强调了准确的临床、影像学和组织学诊断程序对于避免延迟诊断或不适当治疗策略的重要性。建议采用化疗、放疗或两者联合，并进行定期的临床和血液学随访。
