[软腭慢性淋巴细胞白血病]
[Soft palate chronic lymphocytic leukemia].
作者信息
Moumine M, Moudden M-K, El Baaj M, Choumi F, Nassih M, Hadri L
机构信息
Service de chirurgie maxillo-faciale et stomatologie, hôpital militaire Moulay-Ismail, 12000 Meknès, Maroc.
Service de médecine interne, hôpital militaire Moulay-Ismail, 12000 Meknès, Maroc.
出版信息
Rev Stomatol Chir Maxillofac Chir Orale. 2015 Apr;116(2):103-5. doi: 10.1016/j.revsto.2014.10.003. Epub 2014 Oct 28.
INTRODUCTION
Forty percent of non-Hodgkin lymphoma (NHL) are located in extranodal sites. The palatal location of chronic lymphocytic leukemia (CLL) is usually observed at a late stage of the disease.
CASE
We report the case of a 62-year-old male patient managed for 8 years for CLL, having presented with a soft palatal tumor in the last 2 years. The diagnosis of CLL was made by immunohistochemistry. The patient was given 6 courses of chemotherapy combining fludarabine, cyclophosphamide, and rituximab.
DISCUSSION
The diagnosis of CLL requires immunohistochemistry. Chemotherapy is the first line treatment. The complication may be an aggressive lymphoma (Richter).
引言
40%的非霍奇金淋巴瘤（NHL）位于结外部位。慢性淋巴细胞白血病（CLL）发生于腭部的情况通常在疾病晚期出现。
病例
我们报告一例62岁男性患者，患有CLL已接受治疗8年，在过去2年出现软腭肿物。通过免疫组化确诊为CLL。该患者接受了6个疗程的化疗，联合使用氟达拉滨、环磷酰胺和利妥昔单抗。
讨论
CLL的诊断需要免疫组化。化疗是一线治疗方法。其并发症可能是侵袭性淋巴瘤（里氏转化）。
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