Moumine M, Moudden M-K, El Baaj M, Choumi F, Nassih M, Hadri L
Service de chirurgie maxillo-faciale et stomatologie, hôpital militaire Moulay-Ismail, 12000 Meknès, Maroc.
Service de médecine interne, hôpital militaire Moulay-Ismail, 12000 Meknès, Maroc.
Rev Stomatol Chir Maxillofac Chir Orale. 2015 Apr;116(2):103-5. doi: 10.1016/j.revsto.2014.10.003. Epub 2014 Oct 28.
Forty percent of non-Hodgkin lymphoma (NHL) are located in extranodal sites. The palatal location of chronic lymphocytic leukemia (CLL) is usually observed at a late stage of the disease.
We report the case of a 62-year-old male patient managed for 8 years for CLL, having presented with a soft palatal tumor in the last 2 years. The diagnosis of CLL was made by immunohistochemistry. The patient was given 6 courses of chemotherapy combining fludarabine, cyclophosphamide, and rituximab.
The diagnosis of CLL requires immunohistochemistry. Chemotherapy is the first line treatment. The complication may be an aggressive lymphoma (Richter).
40%的非霍奇金淋巴瘤（NHL）位于结外部位。慢性淋巴细胞白血病（CLL）发生于腭部的情况通常在疾病晚期出现。
我们报告一例62岁男性患者，患有CLL已接受治疗8年，在过去2年出现软腭肿物。通过免疫组化确诊为CLL。该患者接受了6个疗程的化疗，联合使用氟达拉滨、环磷酰胺和利妥昔单抗。
CLL的诊断需要免疫组化。化疗是一线治疗方法。其并发症可能是侵袭性淋巴瘤（里氏转化）。
