从大黄的根部提取物质治疗更年期症状：雌激素受体的作用。
Treatment of menopausal symptoms by an extract from the roots of rhapontic rhubarb: the role of estrogen receptors.
机构信息
Molekulare Zellphysiologie & Endokrinologie, Fachrichtung Biologie, Technische Universität Dresden, Dresden, Germany.
出版信息
Chin Med. 2010 Feb 19;5:7. doi: 10.1186/1749-8546-5-7.
Abstract
A dry extract from the roots of rhapontic rhubarb (extract Rheum rhaponticum (L.); ERr) has been commercially available in Germany for over two decades to treat menopausal symptoms. However, the molecular basis of its clinical effectiveness remains obscure. This article reviews the in vitro and in vivo data of its estrogenic actions, particularly those mediated by estrogen receptor-beta (ERbeta).
摘要
从刺叶大黄的根部提取的干提取物（提取物 Rheum rhaponticum (L.); ERr）在德国已经商业化销售了二十多年，用于治疗更年期症状。然而，其临床疗效的分子基础仍然不清楚。本文综述了其雌激素作用的体外和体内数据，特别是由雌激素受体-β（ERβ）介导的作用。
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