Gutiérrez Castrellón P, Polanco Allué I, Salazar Lindo E
Instituto Nacional de Pediatría, Centro de Análisis de la Evidencia COCHRANE-INPed, Red COCHRANE Mexicana, Ministerio de Salud, México.
An Pediatr (Barc). 2010 Mar;72(3):220.e1-220.e20. doi: 10.1016/j.anpedi.2009.11.010. Epub 2010 Feb 19.
Acute gastroenteritis (AG) morbidity and mortality rates in infants and prescholars continue to be high in developing countries. Authors want to develop an evidence-based document that supports decision making regarding AG therapy in infants and children younger than 5 y/o. A systematic review of the literature was performed (May, 2008). Evidence grading was established according to Oxford guidelines and Latin American experts submitted their opinions on the recommendations generated. Oral rehydration solutions are the threatment's keystone for children with AG, showing lesser complications due to therapy than IV fluids. AG is no contraindication of a normal diet. Racecadotril, zinc and smectite can contribute to AG treatment, as well as Lactobacillus GG and Saccharomycces boulardii. No other drugs are recommended. It is recommended to treat children presenting AG with oral rehydration solutions among racecadotril, zinc or smectite as well as some probiotics.
在发展中国家，婴幼儿和学龄前儿童的急性胃肠炎（AG）发病率和死亡率仍然很高。作者希望制定一份基于证据的文件，以支持针对5岁以下婴幼儿AG治疗的决策。2008年5月进行了文献系统综述。根据牛津指南进行证据分级，拉丁美洲专家对所产生的建议发表了意见。口服补液溶液是AG患儿治疗的关键，与静脉输液相比，治疗引起的并发症更少。AG并非正常饮食的禁忌证。消旋卡多曲、锌和蒙脱石有助于AG的治疗，嗜酸乳杆菌GG和布拉酵母菌也有帮助。不推荐使用其他药物。建议用口服补液溶液治疗AG患儿，同时可使用消旋卡多曲、锌或蒙脱石以及一些益生菌。
