Department of Biological Sciences, Florida Atlantic University, Davie, FL 33314, USA.
J Theor Biol. 2010 May 21;264(2):479-89. doi: 10.1016/j.jtbi.2010.02.017. Epub 2010 Feb 18.
Toxicant bioaccumulation poses a risk to many marine mammal populations. Although individual-level toxicology has been the subject of considerable research in several species, we lack a theoretical framework to generalize the results across environments and life histories. Here we formulate a dynamic energy budget model to predict the effects of intra- and interspecific life history variation on toxicant dynamics in marine mammals. Dynamic energy budget theory attempts to describe the most general processes of energy acquisition and utilization in heterotrophs. We tailor the basic model to represent the marine mammal reproductive cycle, and we add a model of toxicant uptake and partitioning to describe vertical transfer of toxicants from mother to offspring during gestation and lactation. We first show that the model predictions are consistent with qualitative patterns reported in empirical studies and previous species-specific modeling studies. Next, we use this model to examine the dependence of offspring toxicant load on birth order, food density, and interspecific life history variation.
有毒物质的生物积累对许多海洋哺乳动物种群构成了威胁。尽管在几个物种中，个体水平的毒理学已经成为相当多研究的主题，但我们缺乏一个理论框架来将结果推广到不同的环境和生活史中。在这里，我们构建了一个动态能量预算模型，以预测种内和种间生活史变异对海洋哺乳动物中毒素动态的影响。动态能量预算理论试图描述异养生物中能量获取和利用的最普遍过程。我们对基本模型进行了调整，以代表海洋哺乳动物的繁殖周期，并且添加了一个有毒物质摄取和分配的模型，以描述在妊娠和哺乳期有毒物质从母亲向后代的垂直转移。我们首先表明，模型预测与经验研究和以前的种特异性建模研究报告的定性模式一致。接下来，我们使用该模型研究了后代中毒物负荷与出生顺序、食物密度和种间生活史变异的关系。
