Division of Urogynecology and Reconstructive Pelvic Surgery, Department of Obstetrics and Gynecology, Women and Infants Hospital, The Warren Alpert Medical School of Brown University, Providence, RI, USA.
Am J Obstet Gynecol. 2010 May;202(5):503.e1-4. doi: 10.1016/j.ajog.2010.01.016. Epub 2010 Feb 20.
We sought to evaluate the association between obesity and vaginal prolapse as well as pelvic organ prolapse symptoms.
This was a cross-sectional study of women referred for urogynecologic care. The exposure was obesity and outcome, stage>or=II prolapse. Secondary outcomes were symptom bother and disease-specific quality of life.
Our study included 721 women. No difference in stage>or=II prolapse was observed between obese (n/N 58/721 [35.8%]) and nonobese (n/N=463/721 [64.2%]) women (50.8% vs 52.7%; P=.62). Obesity was associated with increased distress on the Pelvic Floor Distress Inventory-20 (100 [+/-57.3] vs 87.4 [+/-53.1]; P=.003) due to higher scores on the Colorectal-Anal Distress Inventory-8 (22.9 [+/-21.5] vs 18.3 [+/-19.7]; P=.003) and the Urinary Distress Inventory-6 (48.8 [+/-27] vs 42.4 [+/-26.1]; P=.002).
Obesity was not associated with stage>or=II prolapse but was associated with increased pelvic floor symptoms secondary to urinary and anal incontinence subscales.
我们旨在评估肥胖与阴道脱垂以及盆腔器官脱垂症状之间的关联。
这是一项针对接受泌尿妇科护理的女性的横断面研究。暴露因素为肥胖，结局为脱垂程度≥Ⅱ期。次要结局为症状困扰和疾病特异性生活质量。
我们的研究纳入了 721 名女性。肥胖组（n/N=58/721[35.8%]）和非肥胖组（n/N=463/721[64.2%]）之间的脱垂程度≥Ⅱ期无差异（50.8%比52.7%；P=.62）。肥胖与盆腔器官脱垂严重度问卷-20 得分升高（100[+/-57.3]比 87.4[+/-53.1]；P=.003）有关，这是由于肛肠不适量表-8（22.9[+/-21.5]比 18.3[+/-19.7]；P=.003）和尿失禁困扰量表-6（48.8[+/-27]比 42.4[+/-26.1]；P=.002）得分更高。
肥胖与脱垂程度≥Ⅱ期无关，但与尿失禁和肛门失禁亚量表相关的盆底症状增加有关。
