Biomedical Research Center, Korea Institute of Science and Technology, 39-1 Hawolgok-dong, Seongbuk-gu, Seoul 136-791, Korea.
Chem Commun (Camb). 2010 Mar 14;46(10):1617-9. doi: 10.1039/b923309a. Epub 2010 Jan 12.
Conjugated polymer nanoparticles, produced by in situ colloidal Knoevenagel polymerization, show advantageous properties (bright emission, colloidal/chemical stability and mesoscopic size range) that allow the successful in vivo application to real-time sentinel lymph node mapping in a mouse model.
通过原位胶态 Knoevenagel 聚合制备的共轭聚合物纳米粒子具有优越的性能(明亮的发射、胶体/化学稳定性和介观尺寸范围),使其能够成功应用于活体实时前哨淋巴结示踪在小鼠模型中。