Department of Nutrition, University of California, Davis, USA.
Nutr J. 2010 Feb 23;9:8. doi: 10.1186/1475-2891-9-8.
Metabolic syndrome, a constellation of metabolic risk factors for type 2 diabetes and cardiovascular disease, is one of the fastest growing disease entities in the world. Weight loss is thought to be a key to improving all aspects of metabolic syndrome. Research studies have suggested benefits from diets rich in vegetables and fruits in helping individuals reach and achieve healthy weights.
To evaluate the effects of a ready to serve vegetable juice as part of a calorie-appropriate Dietary Approaches to Stop Hypertension (DASH) diet in an ethnically diverse population of people with Metabolic Syndrome on weight loss and their ability to meet vegetable intake recommendations, and on their clinical characteristics of metabolic syndrome (waist circumference, triglycerides, HDL, fasting blood glucose and blood pressure).A secondary goal was to examine the impact of the vegetable juice on associated parameters, including leptin, vascular adhesion markers, and markers of the oxidative defense system and of oxidative stress.
A prospective 12 week, 3 group (0, 8, or 16 fluid ounces of low sodium vegetable juice) parallel arm randomized controlled trial. Participants were requested to limit their calorie intake to 1600 kcals for women and 1800 kcals for men and were educated on the DASH diet. A total of 81 (22 men & 59 women) participants with Metabolic Syndrome were enrolled into the study. Dietary nutrient and vegetable intake, weight, height, leptin, metabolic syndrome clinical characteristics and related markers of endothelial and cardiovascular health were measured at baseline, 6-, and 12-weeks.
There were significant group by time interactions when aggregating both groups consuming vegetable juice (8 or 16 fluid ounces daily). Those consuming juice lost more weight, consumed more Vitamin C, potassium, and dietary vegetables than individuals who were in the group that only received diet counseling (p < 0.05).
The incorporation of vegetable juice into the daily diet can be a simple and effective way to increase the number of daily vegetable servings. Data from this study also suggest the potential of using a low sodium vegetable juice in conjunction with a calorie restricted diet to aid in weight loss in overweight individuals with metabolic syndrome.
代谢综合征是 2 型糖尿病和心血管疾病代谢风险因素的综合，是全球增长最快的疾病实体之一。人们认为减肥是改善代谢综合征各个方面的关键。研究表明，富含蔬菜和水果的饮食有助于个人达到并保持健康体重。
评估将即食蔬菜汁作为适当热量的 DASH 饮食（Dietary Approaches to Stop Hypertension）的一部分，在代谢综合征患者的种族多样化人群中的作用，以了解其在减肥方面的效果，以及能否达到蔬菜摄入量建议，及其对代谢综合征的临床特征（腰围、甘油三酯、高密度脂蛋白、空腹血糖和血压）的影响。次要目标是检查蔬菜汁对相关参数的影响，包括瘦素、血管黏附标志物以及氧化防御系统和氧化应激的标志物。
前瞻性 12 周、3 组（0、8 或 16 液盎司低钠蔬菜汁）平行臂随机对照试验。要求参与者将热量摄入限制在女性 1600 千卡和男性 1800 千卡，并接受 DASH 饮食教育。共有 81 名（22 名男性和 59 名女性）代谢综合征患者参与了该研究。在基线、6 周和 12 周时测量了饮食营养素和蔬菜摄入量、体重、身高、瘦素、代谢综合征临床特征以及内皮和心血管健康的相关标志物。
当汇总每天饮用 8 或 16 液盎司蔬菜汁的两组时，存在显著的组间时间交互作用。与仅接受饮食咨询的组相比，饮用果汁的个体体重减轻更多，摄入更多的维生素 C、钾和蔬菜（p < 0.05）。
将蔬菜汁纳入日常饮食可以是增加每日蔬菜摄入量的简单有效方法。本研究的数据还表明，在超重代谢综合征患者中，使用低钠蔬菜汁与限制热量饮食结合可能有助于减肥。
