一种用于双极射频消融针道的 tru-cut 活检针：概念验证实验。
A trucut biopsy needle for bipolar radiofrequency ablation of needle tract: a proof-of-concept experiment.
机构信息
Applied Medical Engineering, Helmholtz Institute for Biomedical Engineering, RWTH Aachen University, Aachen, Germany.
出版信息
Eur Radiol. 2010 Aug;20(8):2000-4. doi: 10.1007/s00330-010-1739-1. Epub 2010 Feb 24.
OBJECTIVE
To develop a trucut biopsy needle featuring two electrodes that allow for bipolar radiofrequency (RF) coagulation of the puncture tract.
METHODS
We modified a 14-G trucut biopsy needle to contain two insulated electrodes and connected the device to an RF generator. Biopsies in ex vivo porcine liver and kidney were performed. The puncture tract was coagulated by using different RF energy settings (5 W, 10 W, 20 W). Tissue specimens were dissected along the puncture tract and the coagulation area was macroscopically evaluated. CT-guided in vivo liver and kidney biopsies were performed in two domestic pigs. Lengths of specimens were measured. Post-biopsy contrast-enhanced CT examinations were performed to rule out biopsy-related bleeding. Animals were euthanised and coagulation areas macroscopically explored.
RESULTS
The mean diameters of the coagulated area around the ex vivo biopsy tract were 4.2 +/- 1.1 mm (5 W), 6.0 +/- 2.0 mm (10 W) and 5.2 +/- 0.51 mm (20 W) in liver and 5.0 +/- 0.7 mm (5 W), 6.6 +/- 0.9 (10 W) and 6.0 +/- 2.0 mm (20 W) in kidney. After biopsies CT revealed no bleeding. Mean maximum coagulation diameters were 10.1 +/- 4.6 mm (10 W) in liver and 6.0 +/- 2.5 mm (10 W) in kidney. Mean length of the specimens was 12.2 +/- 4.4 mm in kidney and 11.1 +/- 3.6 mm in liver tissue.
CONCLUSION
Bipolar RF biopsy is a promising tool for tract coagulation after percutaneous biopsy.
目的
开发一种带有两个电极的 tru-cut 活检针，以实现经皮穿刺道的双极射频 (RF) 凝固。
方法
我们对 14-G tru-cut 活检针进行了改进，使其包含两个绝缘电极，并将该装置连接到 RF 发生器。在离体猪肝和肾进行活检。使用不同的 RF 能量设置（5 W、10 W、20 W）对穿刺道进行凝固。沿着穿刺道解剖组织标本，并对凝固区域进行宏观评估。在两只国产猪中进行 CT 引导的经皮肝、肾活检。测量标本的长度。进行活检后增强 CT 检查以排除活检相关出血。对动物实施安乐死，并对凝固区域进行宏观探索。
结果
离体活检道周围凝固区域的平均直径在肝为 4.2 +/- 1.1 mm（5 W）、6.0 +/- 2.0 mm（10 W）和 5.2 +/- 0.51 mm（20 W），在肾为 5.0 +/- 0.7 mm（5 W）、6.6 +/- 0.9（10 W）和 6.0 +/- 2.0 mm（20 W）。活检后 CT 未显示出血。最大凝固直径的平均直径为 10.1 +/- 4.6 mm（10 W）在肝和 6.0 +/- 2.5 mm（10 W）在肾。标本的平均长度在肾为 12.2 +/- 4.4 mm，在肝组织中为 11.1 +/- 3.6 mm。
结论
双极 RF 活检是经皮活检后用于穿刺道凝固的一种有前途的工具。
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