Karkouri Mehdi, Zafad Sadia, Khattab Mohammed, Benjaafar Noureddine, El Kacemi Hanan, Sefiani Sana, Kettani Fouad, Dey Subhojit, Soliman Amr S
Department of Pathology, Centre Hospitalier Universitaire Ibn Rochd, 24 rue Jalal Eddine Essayouti, MA20100 Casablanca, Morocco.
Childs Nerv Syst. 2010 Aug;26(8):1021-7. doi: 10.1007/s00381-010-1097-y. Epub 2010 Feb 24.
Brain tumors are the most common solid tumors diagnosed among children below 15 years worldwide. However, little is known about the profile of pediatric brain tumors in Africa. The purpose of this study was to further elaborate the epidemiological profile of pediatric brain tumors in Africa, specifically Morocco.
A retrospective review was conducted of all patients with primary brain tumors in the age group 0-19 years, from 2003 to 2007, from multiple centers in two cities of Rabat and Casablanca, Morocco. Only patients with histopathological confirmation were included (n = 542). Descriptive epidemiologic profiles were created for the patients by age, sex, and histological subtypes of brain tumors.
Overall medulloblastoma was the most common brain tumor (34.5%), followed by pilocytic astrocytoma (17.3%) and diffuse astrocytoma grade 2 (12.5%). Brain tumors occurred most commonly in 5-9-year age group followed by 10-14-year age group with the former being more common among males and the latter being more common among females. We also found medulloblastoma to be the most common brain tumor in the 0-14-year-olds.
In this rare study focused on pediatric brain tumors in Morocco, most of the findings were consistent with past studies from other parts of the world. However, we found medulloblastoma to be the most common pediatric brain tumor followed by astrocytoma.
脑肿瘤是全球15岁以下儿童中最常见的实体瘤。然而,关于非洲儿童脑肿瘤的情况却知之甚少。本研究的目的是进一步阐述非洲,特别是摩洛哥儿童脑肿瘤的流行病学特征。
对2003年至2007年摩洛哥拉巴特和卡萨布兰卡两个城市多个中心0至19岁原发性脑肿瘤患者进行回顾性研究。仅纳入经组织病理学确诊的患者(n = 542)。根据患者的年龄、性别和脑肿瘤组织学亚型建立描述性流行病学特征。
总体而言,髓母细胞瘤是最常见的脑肿瘤(34.5%),其次是毛细胞型星形细胞瘤(17.3%)和2级弥漫性星形细胞瘤(12.5%)。脑肿瘤最常发生在5至9岁年龄组,其次是10至14岁年龄组,前者在男性中更常见,后者在女性中更常见。我们还发现髓母细胞瘤是0至14岁儿童中最常见的脑肿瘤。
在这项聚焦于摩洛哥儿童脑肿瘤的罕见研究中,大多数发现与世界其他地区过去的研究一致。然而,我们发现髓母细胞瘤是最常见的儿童脑肿瘤,其次是星形细胞瘤。