Mehrotra Ravi, Thomas Shaji, Nair Preeti, Pandya Shruti, Singh Mamta, Nigam Niraj S, Shukla Pankaj
Department of Pathology, Moti Lal Nehru Medical College, Lowther Road, Allahabad, 211001, India.
BMC Res Notes. 2010 Jan 25;3:23. doi: 10.1186/1756-0500-3-23.
The purpose of this study was to determine the prevalence of oral soft tissue lesions in patients and to assess their clinicopathological attributes. 3030 subjects belonging to a semi-urban district of Vidisha in Central India were screened. Patients were examined with an overhead examination light and those who were identified with a questionable lesion underwent further investigations. Statistical analysis was done using the SPSS software.
8.4 percent of the population studied had one or more oral lesions, associated with prosthetic use, trauma and tobacco consumption. With reference to the habit of tobacco use, 635(21%) were smokers, 1272(42%) tobacco chewers, 341(11%) smokers and chewers, while 1464(48%) neither smoked nor chewed. 256 patients were found to have significant mucosal lesions. Of these, 216 cases agreed to undergo scalpel biopsy confirmation. 88 had leukoplakia, 21 had oral submucous fibrosis, 9 showed smoker's melanosis, 6 patients had lichen planus, 17 had dysplasia, 2 patients had squamous cell carcinoma while there was 1 patient each with lichenoid reaction, angina bullosa hemorrhagica, allergic stomatitis and nutritional stomatitis.
The findings in this population reveal a high prevalence of oral soft tissue lesions and a rampant misuse of variety of addictive substances in the community. Close follow up and systematic evaluation is required in this population. There is an urgent need for awareness programs involving the community health workers, dentists and allied medical professionals.
本研究的目的是确定患者口腔软组织病变的患病率,并评估其临床病理特征。对印度中部维迪沙半城市地区的3030名受试者进行了筛查。使用头顶检查灯对患者进行检查,对发现有可疑病变的患者进行进一步检查。使用SPSS软件进行统计分析。
在研究人群中,8.4%的人有一处或多处口腔病变,与假牙使用、创伤和烟草消费有关。关于烟草使用习惯,635人(21%)为吸烟者,1272人(42%)为嚼烟者,341人(11%)既吸烟又嚼烟,而1464人(48%)既不吸烟也不嚼烟。发现256名患者有明显的黏膜病变。其中,216例同意接受手术刀活检确诊。88例为白斑,21例为口腔黏膜下纤维化,9例为吸烟者黑变病,6例为扁平苔藓,17例为发育异常,2例为鳞状细胞癌,同时各有1例患者患有苔藓样反应、出血性大疱性心绞痛、过敏性口炎和营养性口炎。
该人群的研究结果显示口腔软组织病变患病率较高,且社区中存在多种成瘾物质的滥用现象。该人群需要密切随访和系统评估。迫切需要开展由社区卫生工作者、牙医和相关医学专业人员参与的宣传项目。