Aldousari Saad, Sircar Kanishka, Kassouf Wassim
Division of Urology, McGill University Health Center, 1650 Cedar Avenue, Rm. L8-315, Montreal, Quebec, Canada.
Cases J. 2009 Apr 28;2:6647. doi: 10.1186/1757-1626-0002-0000006647.
Plasmacytoid bladder cancer is a rare variant of transitional cell carcinoma. A 57-year-old man was referred to our institution for management of invasive transitional cell carcinoma diagnosed at a peripheral hospital. His complaints were of vague lower abdominal pain with associated urgency and frequency requiring oxybutynin. Metastatic workup was negative and was subsequently scheduled for a radical cystectomy. Routine colonoscopy 3 weeks prior to surgery was negative. Intraoperatively, he was found to have metastatic urothelial cancer involving the cecum and multiple metastatic deposits within the mesentery of the small intestines. He underwent a palliative cystectomy with ileal conduit formation. Final pathology revealed metastatic plasmacytoid variant of urothelial cancer. Histology and immunohistochemistry were compatible with plasmacytoid variant of urothelial cancer. Here we present our case of this rare variant of urothelial cancer with a review of its characteristics.
浆细胞样膀胱癌是移行细胞癌的一种罕见变体。一名57岁男性因在外周医院被诊断为浸润性移行细胞癌而转诊至我院。他的主诉是下腹部隐痛，伴有尿急和尿频，需要使用奥昔布宁治疗。转移灶检查为阴性，随后安排了根治性膀胱切除术。术前3周的常规结肠镜检查结果为阴性。术中发现他患有转移性尿路上皮癌，累及盲肠和小肠系膜内的多个转移灶。他接受了姑息性膀胱切除术并进行了回肠造口术。最终病理显示为尿路上皮癌的转移性浆细胞样变体。组织学和免疫组织化学结果与尿路上皮癌的浆细胞样变体相符。在此，我们报告这例罕见的尿路上皮癌变体病例，并对其特征进行综述。
