McKinlay Audrey, Grace Randolph C, Kaller Christoph P, Dalrymple-Alford John C, Anderson Timothy J, Fink John, Roger Derek
Department of Psychology, University of Canterbury, Christchurch 8140, New Zealand.
Appl Neuropsychol. 2009 Jul;16(3):177-85. doi: 10.1080/09084280903098661.
This study examined whether two tower tasks-the Cambridge Automated Neuropsychological Test Battery "Stockings of Cambridge" (CANTAB-TOL) and the Delis-Kaplan Executive Function System (D-KEFS-TOH), are interchangeable for detecting cognitive deficits in Parkinson's disease (PD) patients. Forty PD patients who met the criteria for this study were assessed with both tasks. The relative contribution of working memory and inhibition was also examined. Relative to controls, PD patients were impaired on the CANTAB-TOL but not the D-KEFS-TOH. Regression analysis which showed that whereas performance on the CANTAB-TOL task was dependent on inhibition and spatial working memory, performance on the D-KEFS-TOH was dependent on spatial working memory only. Only 7% to 24% of the variance between the two tasks was shared. These findings suggest that these tower tasks from two well-established neuropsychological test batteries are not interchangeable.
本研究考察了两项塔楼任务——剑桥自动神经心理测试组套中的“剑桥长袜”（CANTAB-TOL）和德利斯科-卡普兰执行功能系统（D-KEFS-TOH），在检测帕金森病（PD）患者认知缺陷方面是否可相互替代。40名符合本研究标准的PD患者接受了这两项任务的评估。同时还考察了工作记忆和抑制的相对作用。与对照组相比，PD患者在CANTAB-TOL任务上表现受损，但在D-KEFS-TOH任务上未受损。回归分析表明，CANTAB-TOL任务的表现取决于抑制和空间工作记忆，而D-KEFS-TOH任务的表现仅取决于空间工作记忆。两项任务之间只有7%至24%的方差是共享的。这些发现表明，来自两个成熟神经心理测试组套的这些塔楼任务不可相互替代。
