来自三叶木通变种白木通茎部的一种新的三萜皂苷。

A new triterpenoid saponin from the stem of Akebia trifoliata var. australis.

作者信息

Gao Hui-Min, Wang Zhi-Min, Wang Wei-Hao

机构信息

Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China.

出版信息

J Asian Nat Prod Res. 2009 Dec;11(12):1013-8. doi: 10.1080/10286020903213439.

DOI:10.1080/10286020903213439

PMID:20183270

Abstract

A new triterpene glycoside mutongsaponin F (1), together with five known saponins and two known lipids, was isolated from the 70% ethanol extract of the stems of Akebia trifoliata (Thunb.) Koidz. var. australis (Diels) Rehd. Their structures were elucidated on the basis of the spectroscopic analysis and physicochemical properties as 3-beta-[(beta-D-glucopyranosyl-(1-->2)-O-[beta-D-glucopyranosyl-(1-->3)-O-]-alpha-L-arabinopyranosyl)oxy]-30-norolean-12-en-28-oic acid alpha-L-rhamnopyranosyl-(1-->4)-O-beta-D-glucopyranosyl-(1-->6)-O-beta-D-glucopyranosyl ester (1), 3-beta-[(beta-D-glucopyranosyl-(1-->2)-O-[beta-D-glucopyranosyl-(1-->3)-O-]-alpha-L-arabinopyranosyl)oxy]-30-norolean-12-en-28-oic acid (2), leonticin E (3), collinsonidin (4), arjunolic acid 28-O-glucopyranoside (5), asiatic acid 28-O-glucopyranoside (6), soya-cerebroside I (7), and 1-O-alpha-L-galactosyl-(1-->6)-O-beta-D-galactosyl-3-O-hexadecanoyl-glycerol (8), respectively.

摘要

从三叶木通（Akebia trifoliata (Thunb.) Koidz. var. australis (Diels) Rehd.）茎的70%乙醇提取物中分离得到一种新的三萜糖苷木通皂苷F（1），以及五种已知皂苷和两种已知脂质。通过光谱分析和理化性质确定了它们的结构，分别为3-β-[(β-D-吡喃葡萄糖基-(1→2)-O-[β-D-吡喃葡萄糖基-(1→3)-O-]-α-L-阿拉伯吡喃糖基)氧基]-30-降齐墩果-12-烯-28-酸α-L-鼠李吡喃糖基-(1→4)-O-β-D-吡喃葡萄糖基-(1→6)-O-β-D-吡喃葡萄糖基酯（1）、3-β-[(β-D-吡喃葡萄糖基-(1→2)-O-[β-D-吡喃葡萄糖基-(1→3)-O-]-α-L-阿拉伯吡喃糖基)氧基]-30-降齐墩果-12-烯-28-酸（2）、亮叶崖豆藤苷E（3）、柯里森定（4）、阿朱诺酸28-O-吡喃葡萄糖苷（5）、积雪草苷28-O-吡喃葡萄糖苷（6）、大豆脑苷脂I（7）和1-O-α-L-半乳糖基-(1→6)-O-β-D-半乳糖基-3-O-十六烷酰甘油（8）。