纤维蛋白原与孔源性视网膜脱离：一项前瞻性初步研究。
Fibrinogen and rhegmatogenous retinal detachment: a pilot prospective study.
作者信息
Theocharis Ip
机构信息
Ophthalmology Department, Iaso General Hospital, Athens, Greece.
出版信息
Clin Ophthalmol. 2010 Feb 18;4:73-6. doi: 10.2147/opth.s8599.
PURPOSE
To examine the correlation, if any, between fibrinogen plasma levels (FPL) and the clinical features of rhegmatogenous retinal detachment (RRD).
METHODS
FPL were measured preoperatively in 33 patients with primary RRD. Patient characteristics and detachment features such as the numbers of breaks and the extent of the detachment were recorded;
RESULTS
No statistically significant correlation was found between FPL and the number of breaks. A statistically significant correlation was found between FPL and the extent of the RRD, even if the influence of the number of breaks was excluded.
CONCLUSIONS
FPL correlate with retinal detachment extent, which implicates an acute inflammatory response to detachment traumatic phenomenon or a role of the fibrinogen molecule in retinal adhesiveness.
目的
探讨血浆纤维蛋白原水平（FPL）与孔源性视网膜脱离（RRD）临床特征之间是否存在相关性（若有）。
方法
对33例原发性RRD患者术前测定FPL。记录患者特征和脱离特征，如裂孔数量和脱离范围；
结果
未发现FPL与裂孔数量之间存在统计学显著相关性。即使排除裂孔数量的影响，也发现FPL与RRD范围之间存在统计学显著相关性。
结论
FPL与视网膜脱离范围相关，这意味着对脱离创伤现象存在急性炎症反应，或者纤维蛋白原分子在视网膜粘连中起作用。
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