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血流对周围动脉双反转恢复血管壁 MRI 的影响:T2 映射定量分析及与流动敏感 T2 准备反转恢复成像的比较。

Effect of blood flow on double inversion recovery vessel wall MRI of the peripheral arteries: quantitation with T2 mapping and comparison with flow-insensitive T2-prepared inversion recovery imaging.

机构信息

Department of Radiology, Weill Medical College of Cornell University, New York, New York 10016, USA.

出版信息

Magn Reson Med. 2010 Mar;63(3):736-44. doi: 10.1002/mrm.22227.

Abstract

Blood suppression in the lower extremities using flow-reliant methods such as double inversion recovery may be problematic due to slow blood flow. T(2) mapping using fast spin echo (FSE) acquisition was utilized to quantitate the effectiveness of double inversion recovery blood suppression in 13 subjects and showed that 25 +/- 12% of perceived vessel wall pixels in the popliteal arteries contained artifactual blood signal. To overcome this problem, a flow-insensitive T(2)-prepared inversion recovery sequence was implemented and optimal timing parameters were calculated for FSE acquisition. Black blood vessel wall imaging of the popliteal and femoral arteries was performed using two-dimensional T(2)-prepared inversion recovery-FSE in the same 13 subjects. Comparison with two-dimensional double inversion recovery-FSE showed that T(2)-prepared inversion recovery-FSE reduced wall-mimicking blood artifacts that inflated double inversion recovery-FSE vessel wall area measurements in the popliteal artery.

摘要

由于下肢血流缓慢,使用依赖于血流的方法(如双反转恢复)抑制血流可能会出现问题。使用快速自旋回波(FSE)采集的 T2 映射用于定量评估双反转恢复血流抑制在 13 个受试者中的效果,结果显示在腘动脉中感知到的血管壁像素中有 25%±12%存在人为的血液信号。为了克服这个问题,实现了一种对血流不敏感的 T2 准备反转恢复序列,并为 FSE 采集计算了最佳的定时参数。在相同的 13 个受试者中,使用二维 T2 准备反转恢复-FSE 进行了腘动脉和股动脉的黑血血管壁成像。与二维双反转恢复-FSE 的比较表明,T2 准备反转恢复-FSE 减少了壁模拟的血液伪影,这些伪影使双反转恢复-FSE 血管壁面积测量在腘动脉中膨胀。

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