Paediatric Psychosocial Department, Academic Medical Centre/Emma Children's Hospital, Amsterdam, The Netherlands.
Patient Educ Couns. 2010 Nov;81(2):235-44. doi: 10.1016/j.pec.2010.02.003. Epub 2010 Mar 1.
The use of patient reported outcomes (PRO) in routine clinical practice is becoming increasingly common, but there is limited knowledge about the development and implementation of PRO. The objective of the current paper is to provide a thorough description of the development and implementation of a PRO on health related quality of life (HRQOL)--the QLIC-ON PROfile--in clinical paediatric oncology practice.
The development of the QLIC-ON PROfile is explained by elucidating important choices: the HRQOL instrument, the professional that uses the QLIC-ON PROfile, the optimal form of HRQOL feedback and whether or not a clinically important difference is reported. The description of the implementation of the QLIC-ON PROfile focuses on the education and commitment of the professional that uses the QLIC-ON PROfile. Study design and outcome measures are also elaborated on.
Important considerations regarding the development and implementation of PRO interventions are reported. These considerations have also resulted in educational material.
Our study adds to current knowledge of PRO research. This paper can be used as a practical guide for researchers and other professionals, who are interested in setting up PRO interventions in any clinical setting.
患者报告结局（PRO）在常规临床实践中的应用越来越普遍，但对于 PRO 的制定和实施知之甚少。本文的目的是全面描述临床儿科肿瘤实践中健康相关生活质量（HRQOL）PRO——QLIC-ON PROfile 的制定和实施。
通过阐明重要选择来解释 QLIC-ON PROfile 的制定：HRQOL 工具、使用 QLIC-ON PROfile 的专业人员、HRQOL 反馈的最佳形式以及是否报告临床重要差异。对 QLIC-ON PROfile 的实施描述侧重于使用 QLIC-ON PROfile 的专业人员的教育和承诺。还详细说明了研究设计和结果测量。
报告了制定和实施 PRO 干预措施的重要考虑因素。这些考虑因素也产生了教育材料。
本研究增加了 PRO 研究的现有知识。本文可作为对 PRO 干预措施感兴趣的研究人员和其他专业人员在任何临床环境中建立 PRO 干预措施的实用指南。
