Department of Orthodontics, University of Bonn, Bonn, Germany.
J Periodontol. 2010 Mar;81(3):403-11. doi: 10.1902/jop.2009.090498.
It was demonstrated that implants restored according to a platform-switching concept presented less crestal bone loss than implants restored with standard protocols. The aim of this study is to examine differences between the composition of the peri-implant microbiotas associated with implants restored with the platform-switching approach and implants restored with a standard internal connection protocol.
A total of 48 implants were examined in 18 subjects: 33 implants were restored with platform switching, and 15 implants were restored using the traditional approach. Thirty-six months after prosthetic loading, subgingival plaque samples were taken from the mesio- and disto-buccal aspects of each implant and from one tooth adjacent to one of the implants in each subject. The levels of 40 subgingival species were measured using checkerboard DNA-DNA hybridization. Microbiologic parameters were averaged within each subject and across subjects in each clinical group (platform switching versus control) and site category (implants versus teeth) separately. The significance of differences between clinical groups and site categories was determined using the Mann-Whitney test and the Wilcoxon test, respectively.
There were no statistically significant differences between groups for any of the species. The platform-switching group showed a small trend for lower levels of early colonizer members of the Actinomyces, purple and yellow complexes, Campylobacter species, Tannerella forsythia (previously T. forsythensis), and Porphyromonas gingivalis. Teeth and implants presented similar microbial profiles.
The results of the study suggest that the difference in bone crest resorption between implants restored with platform switching compared to traditionally restored implants is not associated with differences in the peri-implant microbiota.
研究表明，采用平台转换概念修复的种植体比采用标准方案修复的种植体引起的牙槽嵴骨吸收更少。本研究旨在检查与采用平台转换方法修复的种植体相关的种植体周围微生物群的组成与采用标准内连接方案修复的种植体之间的差异。
共检查了 18 名受试者的 48 个种植体：33 个种植体采用平台转换修复，15 个种植体采用传统方法修复。在修复体负载 36 个月后，从每个种植体的近中和远颊侧以及每个受试者的一个种植体相邻的一个牙齿中取出龈下菌斑样本。使用斑点杂交 DNA-DNA 杂交法测量 40 种龈下物种的水平。将每个受试者内和每个临床组（平台转换与对照）和部位类别（种植体与牙齿）内的微生物学参数进行平均。使用 Mann-Whitney 检验和 Wilcoxon 检验分别确定临床组和部位类别之间差异的显著性。
在任何物种方面，两组之间均无统计学差异。平台转换组的放线菌、紫色和黄色复合体、弯曲菌属、坦纳拉福赛思菌（以前称为 T. forsythensis）和牙龈卟啉单胞菌等早期定植成员的水平略有降低。牙齿和种植体呈现相似的微生物谱。
研究结果表明，与传统修复的种植体相比，采用平台转换修复的种植体的牙槽嵴骨吸收差异与种植体周围微生物群的差异无关。
