Gao Yan, Fang Li-qun, Zhang Yong, Qian Quan, Li Ya-pin, Xu Cui-ling, Zhang Ye, Yan Lei, Yang Hua, Bai Yan-chen, Yang Hong, Cao Wu-chun, Shu Yue-long
State Key Laboratory for Molecular Virology and Genetic Engineering, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 100052, China.
Zhonghua Liu Xing Bing Xue Za Zhi. 2009 Nov;30(11):1097-101.
To study the spatiotemporal distribution and seasonal characteristics of influenza and to explore its transmission patterns, in the mainland of China.
Spatiotemporal cluster methods and spatial trend surface methods were used to analyze the influenza surveillance data.
There were a summer peak in the south from June to August (RR(paediatric) = 1.31, P < 0.01; RR(internal) = 1.74, P < 0.01) and a winter peak from December to January (RR(paediatric) = 1.45, P < 0.01; RR(internal) = 1.45, P < 0.01) in the northern part of the country, during every epidemic season. Influenza virus in mainland China seemed to spread from the southern to the northern parts of the country, in a progressing way.
In the southern part of the country, it is more important to take prevention and control measurements on influenza from June to August but for the northern part, the key period is from December to January. It is more important to timely identify the variation of the influenza virus, in the southern part of the country.
研究中国内地流感的时空分布和季节特征，并探索其传播模式。
采用时空聚类方法和空间趋势面方法分析流感监测数据。
在每个流行季节，中国北方12月至1月出现冬季高峰（儿童相对危险度（RR）=1.45，P<0.01；成人RR=1.45，P<0.01），南方6月至8月出现夏季高峰（儿童RR=1.31，P<0.01；成人RR=1.74，P<0.01）。中国大陆的流感病毒似乎以渐进的方式从南方传播到北方。
在南方，6月至8月对流感采取防控措施更为重要，而在北方，关键时期是12月至1月。及时识别中国南方流感病毒的变异更为重要。
