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The homeobox protein Prox1 is a negative modulator of ERR{alpha}/PGC-1{alpha} bioenergetic functions.
Genes Dev. 2010 Mar 15;24(6):537-42. doi: 10.1101/gad.1871610. Epub 2010 Mar 1.
2
Genomic convergence among ERRα, PROX1, and BMAL1 in the control of metabolic clock outputs.
PLoS Genet. 2011 Jun;7(6):e1002143. doi: 10.1371/journal.pgen.1002143. Epub 2011 Jun 23.
4
Bile acid receptor agonist GW4064 regulates PPARγ coactivator-1α expression through estrogen receptor-related receptor α.
Mol Endocrinol. 2011 Jun;25(6):922-32. doi: 10.1210/me.2010-0512. Epub 2011 Apr 14.
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Interplay between estrogen-related receptor alpha (ERRalpha) and gamma (ERRgamma) on the regulation of ERRalpha gene expression.
Mol Cell Endocrinol. 2007 Jan 29;264(1-2):128-41. doi: 10.1016/j.mce.2006.11.002. Epub 2006 Dec 8.
8
Estrogen-related receptor alpha is a repressor of phosphoenolpyruvate carboxykinase gene transcription.
J Biol Chem. 2006 Jan 6;281(1):99-106. doi: 10.1074/jbc.M509276200. Epub 2005 Nov 2.

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Mitochondrial quality control in human health and disease.
Mil Med Res. 2024 May 29;11(1):32. doi: 10.1186/s40779-024-00536-5.
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DGAT2 Plays a Crucial Role to Control ESRRA-PROX1 Transcriptional Network to Maintain Hepatic Mitochondrial Sustainability.
Diabetes Metab J. 2024 Sep;48(5):901-914. doi: 10.4093/dmj.2023.0368. Epub 2024 Apr 22.
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Estrogen related receptor alpha: Potential modulator of age-related macular degeneration.
Curr Opin Pharmacol. 2024 Apr;75:102439. doi: 10.1016/j.coph.2024.102439. Epub 2024 Mar 5.
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Dihydroartemisinin suppresses glioma growth by repressing ERRα-mediated mitochondrial biogenesis.
Mol Cell Biochem. 2024 Oct;479(10):2809-2825. doi: 10.1007/s11010-023-04892-z. Epub 2023 Dec 11.
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Fasting-sensitive SUMO-switch on Prox1 controls hepatic cholesterol metabolism.
EMBO Rep. 2023 Oct 9;24(10):e55981. doi: 10.15252/embr.202255981. Epub 2023 Aug 10.
9
Multifaceted Transcriptional Network of Estrogen-Related Receptor Alpha in Health and Disease.
Int J Mol Sci. 2023 Feb 21;24(5):4265. doi: 10.3390/ijms24054265.
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PROX1-mediated epigenetic silencing of contributes to proliferation and glucose metabolism in colorectal cancer.
Int J Biol Sci. 2023 Jan 1;19(1):50-65. doi: 10.7150/ijbs.73530. eCollection 2023.

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1
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk.
Nat Genet. 2010 Feb;42(2):105-16. doi: 10.1038/ng.520. Epub 2010 Jan 17.
3
COUP-TFII regulates the functions of Prox1 in lymphatic endothelial cells through direct interaction.
Genes Cells. 2009 Mar;14(3):425-34. doi: 10.1111/j.1365-2443.2008.01279.x. Epub 2009 Feb 4.
4
Lymphatic endothelial cell identity is reversible and its maintenance requires Prox1 activity.
Genes Dev. 2008 Dec 1;22(23):3282-91. doi: 10.1101/gad.1727208.
5
Prox1 physically and functionally interacts with COUP-TFII to specify lymphatic endothelial cell fate.
Blood. 2009 Feb 19;113(8):1856-9. doi: 10.1182/blood-2008-03-145789. Epub 2008 Sep 24.
6
Transcriptional control of energy homeostasis by the estrogen-related receptors.
Endocr Rev. 2008 Oct;29(6):677-96. doi: 10.1210/er.2008-0017. Epub 2008 Jul 29.
9
ERRgamma directs and maintains the transition to oxidative metabolism in the postnatal heart.
Cell Metab. 2007 Jul;6(1):13-24. doi: 10.1016/j.cmet.2007.06.007.
10
Genome-wide orchestration of cardiac functions by the orphan nuclear receptors ERRalpha and gamma.
Cell Metab. 2007 May;5(5):345-56. doi: 10.1016/j.cmet.2007.03.007.

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