University of Dundee, UK.
Nat Methods. 2010 Mar;7(3 Suppl):S16-25. doi: 10.1038/nmeth.1434.
Software for visualizing sequence alignments and trees are essential tools for life scientists. In this review, we describe the major features and capabilities of a selection of stand-alone and web-based applications useful when investigating the function and evolution of a gene family. These range from simple viewers, to systems that provide sophisticated editing and analysis functions. We conclude with a discussion of the challenges that these tools now face due to the flood of next generation sequence data and the increasingly complex network of bioinformatics information sources.
用于可视化序列比对和树的软件是生命科学家的基本工具。在这篇综述中，我们描述了一系列独立的和基于网络的应用程序的主要功能和特性，这些应用程序在研究基因家族的功能和进化时非常有用。这些应用程序的范围从简单的查看器到提供复杂编辑和分析功能的系统。最后，我们讨论了由于下一代测序数据的大量涌现以及生物信息学信息源日益复杂的网络，这些工具现在面临的挑战。
