Veluchamy Alaguraj, Mary Sujitha, Acharya Vishal, Mehta Preethi, Deva Taru, Krishnaswamy Sankaran
Center of Excellence in Bioinformatics, School of biotechnology, Madurai Kamaraj University, Madurai, India.
Bioinformation. 2009 Sep 6;4(2):80-3. doi: 10.6026/97320630004080.
The HNH Database is a collection and sequence-based classification of HNH domain proteins. The database contains about 1913 HNH domain containing proteins, and is classified into 10 subsets based on the sequence pattern. Each of these subsets has unique signature sequences. We have shown a correlation between the subset combination and their domain association and function. Functional divergence of this domain may be due to the combination of these conserved patterns and the large variations in the non-conserved regions. HNHDb is freely available at http://bicmku.in:8081/hnh.
HNH数据库是一个基于HNH结构域蛋白的收集和序列分类。该数据库包含约1913个含有HNH结构域的蛋白，并根据序列模式分为10个子集。这些子集中的每一个都有独特的特征序列。我们已经展示了子集组合与其结构域关联和功能之间的相关性。该结构域的功能差异可能是由于这些保守模式的组合以及非保守区域的巨大变化。HNHDb可在http://bicmku.in:8081/hnh免费获取。
