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糖生物学综述:碳水化合物、凝集素及其在癌症治疗中的意义。

A glycobiology review: carbohydrates, lectins and implications in cancer therapeutics.

机构信息

Department of Biology and Center for Cancer and Developmental Biology, California State University Northridge, 18111 Nordhoff Street, Northridge, CA 91330-8303, USA.

出版信息

Acta Histochem. 2011 May;113(3):236-47. doi: 10.1016/j.acthis.2010.02.004. Epub 2010 Mar 2.

Abstract

This review is intended for general readers who would like a basic foundation in carbohydrate structure and function, lectin biology, and the implications of glycobiology in human health and disease, particularly in cancer therapeutics. These topics are among the hundreds included in the field of glycobiology and are treated here because they form the cornerstone of glycobiology or the focus of many advances in this rapidly expanding field.

摘要

这篇综述面向希望对碳水化合物结构和功能、凝集素生物学以及糖生物学在人类健康和疾病(特别是癌症治疗)中的意义有基本了解的一般读者。这些主题是糖生物学领域的数百个主题之一,之所以在这里讨论,是因为它们构成了糖生物学的基石,或者是这个快速发展领域中许多进展的重点。

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