口腔黏膜下纤维化患者唾液α-L-岩藻糖苷酶和唾液酸的分析
Analysis of salivary alpha-L-fucosidase and salic acid among oral sub-mucous fibrosis patients.
作者信息
Mitra Sayan, Gujjarlapudi Satish, Abdul Nishath Sayed, Singh Pallavi, Giri Debanti, Pansheriya Ekta, Makkad Ramanpal Singh
机构信息
Department of Oral Medicine and Radiology, RKDF Dental College, Bhopal, M.P., India.
DMD,MBS,BDS, Associate Dentist, Familia dental, 804 S Green River road, Evansville, IN 47715.
出版信息
Bioinformation. 2024 Jun 30;20(6):669-673. doi: 10.6026/973206300200669. eCollection 2024.
The salivary concentrations of alpha L fucosidase (AFU) and salic acid (SA) in oral submucous fibrosis patients and compare it with healthy controls is of interest to dentists. 40 patients of OSMF and 40 healthy controls were included. Estimation of AFU and SA in saliva and serum was carried out in every patient. The serum level of AFU was 37.4±26.8 in OSMF patients and saliva level of AFU was 35.4±14.5. The serum level of AFU was 19.2±4.3 in control group and saliva level of AFU was 35.4±14.5 in control group. The serum level of SA was 20.32±2.71 in OSMF patients and saliva level of SA was 18.21±2.40. The serum level of SA was 4.89 ±1.17 in control group and saliva level of SA was 3.13 ±1.04 in control group. Estimation of concentration of SA and AFU in saliva can be effective biomarker in diagnosis of OSMF.
口腔黏膜下纤维化患者唾液中α-L-岩藻糖苷酶（AFU）和水杨酸（SA）的浓度及其与健康对照的比较是牙医感兴趣的。纳入了40例口腔黏膜下纤维化患者和40例健康对照。对每位患者的唾液和血清中的AFU和SA进行了测定。口腔黏膜下纤维化患者血清中AFU水平为37.4±26.8，唾液中AFU水平为35.4±14.5。对照组血清中AFU水平为19.2±4.3，对照组唾液中AFU水平为35.4±14.5。口腔黏膜下纤维化患者血清中SA水平为20.32±2.71，唾液中SA水平为18.21±2.40。对照组血清中SA水平为4.89±1.17，对照组唾液中SA水平为3.13±1.04。唾液中SA和AFU浓度的测定可作为口腔黏膜下纤维化诊断的有效生物标志物。
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