Casas-Agustench Patricia, Bulló Mònica, Salas-Salvadó Jordi
Human Nutrition Unit, Hospital Universitari Sant Joan de Reus, IISPV, Universitat Rovira i Virgili, Sant Llorenç 21, 43201 Reus, Spain.
Asia Pac J Clin Nutr. 2010;19(1):124-30.
The beneficial effects of nut consumption on cardiovascular disease (CVD) have been widely documented. These protective effects are mainly attributed to the role of nuts in the metabolism of lipids and lipoproteins. As chronic inflammation is a key early stage in the atherosclerotic process that predicts future CVD events and is closely related to the pathogenesis of insulin resistance, many recent studies have focused on the potential effect of nut consumption on inflammation and insulin resistance. Through different mechanisms, some components of nuts such as magnesium, fiber, alpha-linolenic acid, L-arginine, antioxidants and MUFA may protect against inflammation and insulin resistance. This review evaluates the epidemiologic and experimental evidence in humans demonstrating an association between nut consumption and these two emergent cardio-protective mechanisms.
食用坚果对心血管疾病（CVD）的有益影响已得到广泛记载。这些保护作用主要归因于坚果在脂质和脂蛋白代谢中的作用。由于慢性炎症是动脉粥样硬化过程中的关键早期阶段，可预测未来的心血管疾病事件，且与胰岛素抵抗的发病机制密切相关，因此最近许多研究都集中在食用坚果对炎症和胰岛素抵抗的潜在影响上。通过不同机制，坚果的某些成分，如镁、纤维、α-亚麻酸、L-精氨酸、抗氧化剂和单不饱和脂肪酸，可能有助于预防炎症和胰岛素抵抗。本综述评估了人体流行病学和实验证据，以证明食用坚果与这两种新出现的心脏保护机制之间的关联。
