Skafida Evangelia, Grammatoglou Xanthippi, Glava Chryssoula, Zissis Dimitrios, Paschalidis Nikolaos, Katsamagkou Eleftheria, Firfiris Nikolaos, Vasilakaki Thivi
Department of Pathology, "Tzaneion" General Hospital of Piraeus, Zanni & Afentouli 1, Piraeus-Greece.
Cases J. 2010 Feb 1;3:41. doi: 10.1186/1757-1626-3-41.
Adenosquamous carcinoma of the pancreas is a rare variant of pancreatic exocrine carcinoma. We report a case of 70 year old man who came to our hospital with abdominal pain, anorexia and jaundice. Imaging of the abdomen showed a mass in the region of the head of the pancreas. Histological evaluation of the pancreatic tumor showed an adenosquamous carcinoma which was extensively infiltrative with perineural invasion, involvement of peripancreatic lymph nodes and all the thickness of the duodenum wall. The tumor exhibited a biphasic malignant growth identified as well to moderate differentiated adenocarcinoma and well to poorly differentiated squamous cell carcinoma.
胰腺腺鳞癌是胰腺外分泌癌的一种罕见变异型。我们报告一例70岁男性患者，因腹痛、厌食和黄疸前来我院就诊。腹部影像学检查显示胰腺头部区域有一个肿块。胰腺肿瘤的组织学评估显示为腺鳞癌，具有广泛浸润性，伴有神经周围侵犯、胰周淋巴结受累以及十二指肠壁全层受累。肿瘤呈现出双相恶性生长，表现为中分化腺癌和高分化至低分化鳞状细胞癌。
