1st Propaedeutic Surgery Department, AHEPA University General Hospital of Thessaloniki, Aristotle University of Thessaloniki, Thessaloniki, Greece.
1st Propaedeutic Internal Medicine Department, AHEPA University General Hospital of Thessaloniki, Aristotle University of Thessaloniki, Thessaloniki, Greece.
J Med Case Rep. 2022 Oct 30;16(1):395. doi: 10.1186/s13256-022-03610-5.
Among the total reported cases of pancreatic duct adenocarcinomas, around 1-2.9% are adenosquamous carcinomas of the pancreas. Due to limited data, preoperative diagnosis is a great challenge for physicians, and it is usually set post-operational, based on the pathologist report. We operated on two cases of adenosquamous carcinoma of the pancreas, which we present alongside the operation and treatment planning.
A 69-year-old Caucasian female and a 63-year-old Caucasian male presented themselves with jaundice in our department. The abdomen computed tomography and magnetic resonance imaging scans revealed lesions of the pancreas. A pancreas-duodenumectomy was performed in both patients, and the post-operational histology analysis revealed adenosquamous carcinoma of the pancreas head. The patients were discharged in good condition and received further chemotherapy treatment after surgery.
Two case reports of adenosquamous carcinoma of the pancreas are described here, which both underwent surgery resection. The limited available literature on this topic substantially limits the knowledge and guidance on treatment. A summarization of the available literature is attempted, alongside a description of possible fields of future research.
在已报告的胰腺导管腺癌病例中，约有 1%-2.9%为胰腺腺鳞癌。由于数据有限，术前诊断对医生来说是一个巨大的挑战，通常是根据病理报告在术后确定的。我们对两例胰腺腺鳞癌患者进行了手术，并结合手术和治疗计划进行了介绍。
一名 69 岁的白人女性和一名 63 岁的白人男性因黄疸到我科就诊。腹部 CT 和磁共振成像扫描显示胰腺有病变。两名患者均接受了胰十二指肠切除术，术后组织学分析显示为胰腺头部的腺鳞癌。患者恢复良好，术后接受了进一步的化疗。
本文描述了两例胰腺腺鳞癌病例，均接受了手术切除。由于该主题的可用文献有限，极大地限制了对治疗的了解和指导。我们尝试对现有文献进行总结，并描述未来可能的研究领域。
