Artal Raquel, Agreda Beatriz, Serrano Eduardo, Alfonso José I, Vallés Héctor
Hospital Clínico Universitario Lozano Blesa, Zaragoza, España.
Acta Otorrinolaringol Esp. 2010 Jul-Aug;61(4):301-5. doi: 10.1016/j.otorri.2010.01.003. Epub 2010 Mar 6.
Mucormycosis is a serious condition, usually acute and often fatal, It presents in its most aggressive form in debilitated hosts, usually with diabetic ketoacidosis or immunosuppression. As otolaryngologists, we must diagnose it as early as possible, establish early treatment with amphotericin B and perform a surgical manoeuvre to obtain infection-free margins. It is rare and largely unknown, contributing to delayed diagnosis. It should be borne in mind due to the great increase of population with risk factors. We report eight cases seen in our hospital in recent years (1997-2007). Four were female and four male, aged between 36 and 86 years. The mean age at diagnosis was 57 and all had a predisposing factor. The treatment carried out was that of the underlying disease, systemic antifungal therapy and surgery.
毛霉病是一种严重的疾病，通常为急性，且往往致命。它在身体虚弱的宿主中以最具侵袭性的形式出现，通常伴有糖尿病酮症酸中毒或免疫抑制。作为耳鼻喉科医生，我们必须尽早诊断，尽早使用两性霉素B进行治疗，并进行手术操作以获得无感染切缘。它很罕见且很大程度上不为人知，这导致了诊断延迟。鉴于具有危险因素的人群大幅增加，应予以重视。我们报告了近年来（1997 - 2007年）在我院见到的8例病例。4例为女性，4例为男性，年龄在36至86岁之间。诊断时的平均年龄为57岁，且所有患者都有一个诱发因素。所进行的治疗包括治疗基础疾病、全身抗真菌治疗和手术。
