Sheridan Carolin J, Matuz Tamara, Draganova Rossitza, Eswaran Hari, Preissl Hubert
Department of Obstetrics and Gynecology, University of Arkansas for Medical Sciences, 4301 W. Markham # 518, Little Rock, Arkansas 72205.
Infant Child Dev. 2010;19(1):80-93. doi: 10.1002/icd.657.
Fetal magnetoencephalography (fMEG) is the only non-invasive method for investigating evoked brain responses and spontaneous brain activity generated by the fetus in utero. Fetal auditory as well as visual evoked fields have been successfully recorded in basic stimulus-response studies. Moreover, paradigms investigating precursors for cognitive development, such as habituation and mismatch response have been applied successfully with fMEG. These and other studies have shown that the prenatal stage of life could be an important indicator for later cognitive development. This review addresses the achievements of fMEG and constructively discusses its challenges. It concludes with proposals for future studies as well as with designated new applications. Fetal MEG is a promising, and to date it is the only non-invasive approach for the prenatal assessment of precursors for cognitive development. Future fMEG studies might even enable the diagnosis of developmental delays. Furthermore, fMEG could be critical for the implementation and evaluation of fetal intervention programs in at-risk populations.
胎儿脑磁图（fMEG）是唯一一种用于研究子宫内胎儿诱发脑反应和自发脑活动的非侵入性方法。在基础刺激-反应研究中，已成功记录到胎儿听觉和视觉诱发场。此外，研究认知发展前体的范式，如习惯化和失配反应，已通过fMEG成功应用。这些研究及其他研究表明，生命的产前阶段可能是后期认知发展的重要指标。本综述阐述了fMEG的成就，并建设性地讨论了其面临的挑战。最后提出了未来研究的建议以及指定的新应用。胎儿脑磁图是一种很有前景的方法，迄今为止，它是用于产前评估认知发展前体的唯一非侵入性方法。未来的fMEG研究甚至可能实现发育迟缓的诊断。此外，fMEG对于高危人群胎儿干预项目的实施和评估可能至关重要。
