University of California, Irvine, Irvine Beckman Laser Institute, Department of Biomedical Engineering, Irvine, California 92612, USA.
J Biomed Opt. 2010 Jan-Feb;15(1):016029. doi: 10.1117/1.3302806.
We demonstrate the use of Doppler variance (standard deviation) imaging for 3-D in vivo angiography in the human eye. In addition to the regular optical Doppler tomography velocity and structural images, we use the variance of blood flow velocity to map the retina and choroid vessels. Variance imaging is subject to bulk motion artifacts as in phase-resolved Doppler imaging, and a histogram-based method is proposed for bulk-motion correction in variance imaging. Experiments were performed to demonstrate the effectiveness of the proposed method for 3-D vasculature imaging of human retina and choroid.
我们展示了多普勒方差(标准差)成像在人眼 3D 体内血管造影中的应用。除了常规的光学多普勒层析速度和结构图像外,我们还使用血流速度的方差来绘制视网膜和脉络膜血管图。方差成像是受像散分辨多普勒成像中体动伪影的影响,我们提出了一种基于直方图的方法来校正方差成像中的体动伪影。实验证明了该方法在人眼视网膜和脉络膜 3D 血管成像中的有效性。