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General and efficient copper-catalyzed three-component coupling reaction towards imidazoheterocycles: one-pot synthesis of alpidem and zolpidem.

作者信息

Chernyak Natalia, Gevorgyan Vladimir

机构信息

Department of Chemistry, University of Illinois at Chicago, 845 West Taylor Street, Room 4500, Chicago, IL 60607, USA.

出版信息

Angew Chem Int Ed Engl. 2010 Apr 1;49(15):2743-6. doi: 10.1002/anie.200907291.

DOI:10.1002/anie.200907291
PMID:20213787
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3516864/
Abstract
摘要

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Indium-catalyzed highly efficient three-component coupling of aldehyde, alkyne, and amine via C-H bond activation.铟催化的通过C-H键活化实现醛、炔烃和胺的高效三组分偶联反应。
J Org Chem. 2009 Jun 5;74(11):4364-7. doi: 10.1021/jo900507v.
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Iron-catalyzed ligand-free three-component coupling reactions of aldehydes, terminal alkynes, and amines.
脂肪酶催化的咪唑稠合氮桥头杂环的合成及其抗真菌和抗菌生物活性。
RSC Adv. 2024 Feb 7;14(8):5037-5044. doi: 10.1039/d3ra07145f.
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Advances in Selected Heterocyclization Methods.特定杂环化方法的进展
Synlett. 2023 Aug;34(13):1554-1562. doi: 10.1055/s-0042-1751429. Epub 2023 Mar 10.
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Photocatalytic sequential C-H functionalization expediting acetoxymalonylation of imidazo heterocycles.光催化顺序C-H官能化加速咪唑杂环的乙酰氧基丙二酸酯化反应
Beilstein J Org Chem. 2023 May 12;19:666-673. doi: 10.3762/bjoc.19.48. eCollection 2023.
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Antibiotics (Basel). 2022 Nov 22;11(12):1680. doi: 10.3390/antibiotics11121680.
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