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2 型糖尿病男性患者坚持地中海饮食与勃起功能障碍的关系。

Adherence to Mediterranean diet and erectile dysfunction in men with type 2 diabetes.

机构信息

Division of Urology, Department of Geriatrics and Metabolic Diseases, Second University of Naples, Naples, Italy.

出版信息

J Sex Med. 2010 May;7(5):1911-7. doi: 10.1111/j.1743-6109.2010.01713.x. Epub 2010 Feb 25.

DOI:10.1111/j.1743-6109.2010.01713.x
PMID:20214716
Abstract

INTRODUCTION

There are no reported studies assessing the relation between diet and erectile dysfunction (ED) in men with diabetes.

AIM

In the present study, we explored the relation between consumption of a Mediterranean-type diet and ED in a population of type 2 diabetic men.

METHODS

Patients with type 2 diabetes were enrolled if they had a diagnosis of type 2 diabetes for at least six months but less than 10 years, age 35-70 years, body mass index (BMI) of 24 or higher, HbA1c of 6.5% or higher, treatment with diet or oral drugs. All diabetic patients were invited to complete a food-frequency questionnaire and self-report measures of sexual function. A total of 555 (90.8%) of the 611 diabetic men completed both questionnaires and were analyzed in the present study.

MAIN OUTCOME MEASURES

Adherence to a Mediterranean diet was assessed by a 9-point scale that incorporated the salient characteristics of this diet (range of scores, 0-9, with higher scores indicating greater adherence). ED was assessed with the International Index of Erectile Function-5.

RESULTS

Diabetic men with the highest scores (6-9) had lower BMI, waist circumference, and waist-to-hip ratio, a lower prevalence of obesity and metabolic syndrome, a higher level of physical activity, and better glucose and lipid profiles than the diabetic men who scored <3 points on the scale. The proportion of sexually active men showed a significant increase across tertiles of adherence to Mediterranean diet (from 65.1% to 74.4%, P = 0.01). Moreover, men with the highest score of adherence were more likely to have a lower prevalence of global ED (51.9% vs. 62%, P = 0.01) and severe ED (16.5% vs. 26.4%, P = 0.01) as compared with low adherers.

CONCLUSIONS

In men with type 2 diabetes, greater adherence to Mediterranean diet is associated with a lower prevalence of ED.

摘要

简介

目前尚无研究评估糖尿病男性的饮食与勃起功能障碍(ED)之间的关系。

目的

在本研究中,我们探讨了 2 型糖尿病男性人群中地中海饮食的摄入与 ED 之间的关系。

方法

如果患者患有 2 型糖尿病至少 6 个月但不超过 10 年、年龄在 35-70 岁之间、体重指数(BMI)≥24、糖化血红蛋白(HbA1c)≥6.5%、接受饮食或口服药物治疗,则将其纳入研究。所有糖尿病患者均被邀请填写食物频率问卷和性功能自评量表。共有 611 名糖尿病男性中的 555 名(90.8%)完成了两份问卷,并在本研究中进行了分析。

主要观察指标

采用 9 分制评估地中海饮食的依从性,该评分纳入了这种饮食的显著特征(评分范围 0-9,得分越高表示依从性越高)。ED 采用国际勃起功能指数-5 进行评估。

结果

在评分最高(6-9 分)的糖尿病男性中,BMI、腰围和腰臀比较低,肥胖和代谢综合征的患病率较低,身体活动水平较高,血糖和血脂水平较好。随着对地中海饮食依从性的三分位分层,活跃性生活的男性比例显著增加(从不依从者的 65.1%增加到依从者的 74.4%,P=0.01)。此外,与低依从者相比,依从性评分最高的男性患全球 ED(51.9%比 62%,P=0.01)和重度 ED(16.5%比 26.4%,P=0.01)的患病率较低。

结论

在 2 型糖尿病男性中,较高的地中海饮食依从性与 ED 的较低患病率相关。

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