Genomics Coordination Center, Department of Genetics, University Medical Center Groningen and University of Groningen, Groningen, The Netherlands.
Genome Biol. 2010;11(3):R27. doi: 10.1186/gb-2010-11-3-r27. Epub 2010 Mar 9.
We present an extensible software model for the genotype and phenotype community, XGAP. Readers can download a standard XGAP (http://www.xgap.org) or auto-generate a custom version using MOLGENIS with programming interfaces to R-software and web-services or user interfaces for biologists. XGAP has simple load formats for any type of genotype, epigenotype, transcript, protein, metabolite or other phenotype data. Current functionality includes tools ranging from eQTL analysis in mouse to genome-wide association studies in humans.
我们提出了一个用于基因型和表型群体的可扩展软件模型,即 XGAP。读者可以下载标准的 XGAP(http://www.xgap.org),也可以使用 MOLGENIS 自动生成自定义版本,该软件具有与 R 软件和 Web 服务的编程接口,以及针对生物学家的用户界面。XGAP 具有用于任何类型基因型、表观基因型、转录本、蛋白质、代谢物或其他表型数据的简单加载格式。当前的功能包括从老鼠的 eQTL 分析到人类的全基因组关联研究等各种工具。