Universities of Geneva and Lausanne, Switzerland.
Ann Pharmacother. 2010 Apr;44(4):650-7. doi: 10.1345/aph.1M537. Epub 2010 Mar 9.
Six pioneer physicians-pharmacists quality circles (PPQCs) located in the Swiss canton of Fribourg (administratively corresponding to a state in the US) were under the responsibility of 6 trained community pharmacists moderating the prescribing process of 24 general practitioners (GPs). PPQCs are based on a multifaceted collaborative process mediated by community pharmacists for improving compliance with clinical guidelines within GPs' prescribing practices.
To assess, over a 9-year period (1999-2007), the cost-containment impact of the PPQCs.
The key elements of PPQCs are a structured continuous quality improvement and education process; local networking; feedback of comparative and detailed data regarding costs, drug choice, and frequency of prescribed drugs; and structured independent literature review for interdisciplinary continuing education. The data are issued from the community pharmacy invoices to the health insurance companies. The study analyzed the cost-containment impact of the PPQCs in comparison with GPs working in similar conditions of care without particular collaboration with pharmacists, the percentage of generic prescriptions for specific cardiovascular drug classes, and the percentage of drug costs or units prescribed for specific cardiovascular drugs.
For the 9-year period, there was a 42% decrease in the drug costs in the PPQC group as compared to the control group, representing a $225,000 (USD) savings per GP only in 2007. These results are explained by better compliance with clinical and pharmacovigilance guidelines, larger distribution of generic drugs, a more balanced attitude toward marketing strategies, and interdisciplinary continuing education on the rational use of drugs.
The PPQC work process has yielded sustainable results, such as significant cost savings, higher penetration of generics and reflection on patient safety, and the place of "new" drugs in therapy. The PPQCs may also constitute a solid basis for implementing more comprehensive collaborative programs, such as medication reviews, adherence-enhancing interventions, or disease management approaches.
在瑞士弗里堡州(行政上相当于美国的一个州),六名先驱医生-药剂师质量圈(PPQC)由六名经过培训的社区药剂师负责,他们对 24 名全科医生(GP)的处方过程进行调节。PPQC 基于一个多方面的协作过程,由社区药剂师进行调解,以改善 GP 处方实践中对临床指南的遵守情况。
在 9 年期间(1999-2007 年)评估 PPQC 的成本控制影响。
PPQC 的关键要素是结构化的持续质量改进和教育过程;本地网络;关于成本、药物选择和规定药物频率的比较和详细数据的反馈;以及针对跨学科继续教育的结构化独立文献综述。这些数据来自社区药房向健康保险公司开具的发票。该研究分析了与没有与药剂师特别合作的情况下提供类似护理条件的 GP 相比,PPQC 在特定心血管药物类别的通用处方比例和特定心血管药物的药物成本或规定单位百分比方面的成本控制影响。
在 9 年期间,PPQC 组的药物成本下降了 42%,仅在 2007 年,每个 GP 就节省了 22.5 万美元(美元)。这些结果解释了更好地遵守临床和药物警戒指南、更大比例的通用药物分配、对营销策略的更平衡态度以及关于合理使用药物的跨学科继续教育。
PPQC 工作流程产生了可持续的结果,例如显著的成本节约、更高的通用药物渗透率和对患者安全的反思,以及“新”药物在治疗中的地位。PPQC 还可能为实施更全面的协作计划奠定坚实的基础,例如药物审查、增强依从性的干预措施或疾病管理方法。