Department of Physics and School of Engineering and Applied Sciences, Harvard University, Cambridge, Massachusetts 02139, USA.
Biomicrofluidics. 2009 Sep 8;3(3):34104. doi: 10.1063/1.3224669.
Precise patterning of metals is required for diverse microfluidic and microelectromechanical system (MEMS) applications ranging from the separation of proteins to the manipulation of single cells and drops of water-in-oil emulsions. Here we present a very simple, inexpensive method for fabricating micropatterned electrodes. We deposit a thin metal layer of controlled thickness using wet chemistry, thus eliminating the need for expensive equipment typically required for metal deposition. We demonstrate that the resulting deposited metal can be used to fabricate functional electrodes: The wet-deposited metal film can sustain patterning by photolithography down to micron-sized features required for MEMS and microfluidic applications, and its properties are suitable for operative electrodes used in a wide range of microfluidic applications for biological studies.
为了满足从蛋白质分离到单细胞操作和油水乳液滴操控等各种微流控和微机电系统 (MEMS) 应用的需求,需要对金属进行精确的图案化处理。在这里,我们提出了一种非常简单、廉价的制造微图案化电极的方法。我们使用湿法化学沉积一层可控厚度的薄金属层,从而消除了通常用于金属沉积的昂贵设备的需求。我们证明,所得到的沉积金属可用于制造功能电极:湿沉积金属膜可以通过光刻进行图案化,图案的最小特征尺寸可达用于 MEMS 和微流控应用所需的微米级,其性能适合于广泛的生物研究微流控应用中使用的操作电极。